|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse INHBA ORF mammalian expression plasmid, C-GFPSpark tag||MG50659-ACG|
|Mouse INHBA ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50659-ACR|
|Mouse INHBA ORF mammalian expression plasmid, C-Flag tag||MG50659-CF|
|Mouse INHBA ORF mammalian expression plasmid, C-His tag||MG50659-CH|
|Mouse INHBA ORF mammalian expression plasmid, C-Myc tag||MG50659-CM|
|Mouse INHBA ORF mammalian expression plasmid, C-HA tag||MG50659-CY|
|Mouse INHBA Gene cDNA clone plasmid||MG50659-M|
|Mouse INHBA ORF mammalian expression plasmid, N-Flag tag||MG50659-NF|
|Mouse INHBA ORF mammalian expression plasmid, N-His tag||MG50659-NH|
|Mouse INHBA ORF mammalian expression plasmid, N-Myc tag||MG50659-NM|
|Mouse INHBA ORF mammalian expression plasmid, N-HA tag||MG50659-NY|
|Mouse INHBA natural ORF mammalian expression plasmid||MG50659-UT|
|Learn more about expression Vectors|
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two monomers are linked to one another by a single disulfide bond. Activin is composed of two β subunits, βA βA (activin A), βB βB (activin B), or βA βB (activin AB). Inhibin is composed of an alpha and one of two β subunits, βA (inhibin A) or βB (inhibin B). Activins are produced in many cell types and organs, such as gonads, pituitary gland, and placenta. In the ovarian follicle, activin increases FSH binding and FSH-induced aromatization. It participates in androgen synthesis enhancing LH action in the ovary and testis. In the male, activin enhances spermatogenesis. In addition, Activin plays a role in wound repair and skin morphogenesis. Activin is strongly expressed in wounded skin, and overexpression of activin in epidermis of transgenic mice improves wound healing and enhances scar formation. Activin also regulates the morphogenesis of branching organs such as the prostate, lung, and kidney. There is also evidence showed that lack of activin during development results in neural developmental defects.