IL23 Receptor qPCR Primer Pairs, Mouse

Cat: MP201174
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IL23 Receptor qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
IL23 Receptor qPCR Primer Pairs, Mouse Alternative Names
IL-23R qPCR Primer Pairs, Mouse
IL23 Receptor Background Information

IL23R, also known as IL23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells. IL23R associates with IL12RB1 to form the interleukin-23 receptor. It binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. Genetic variations in IL23R are associated with inflammatory bowel disease type 17 (IBD17). IBD17 is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. Genetic variations in IL23R also can cause susceptibility to psoriasis type 7.

Full Name
interleukin 23 receptor
References
  • Duerr RH, et al. (2006) A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science. 314(5804):1461-3.
  • Cargill M, et al. (2007) A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet. 80(2):273-90.
  • Dubinsky MC, et al. (2007) IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease. Inflamm Bowel Dis. 13(5):511-5.
  • Tremelling M, et al. (2007) IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease. Gastroenterology. 132(5):1657-64.
  • IL23 Receptor qPCR Primer Pairs, Rhesus, Related Products

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    IL23 Receptor cDNA ORF Clone in Cloning Vector, Rhesus CG90123-G
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    IL23 Receptor cDNA ORF Clone, Rhesus, C-His tag CG90123-CH
    IL23 Receptor cDNA ORF Clone, Rhesus, N-His tag CG90123-NH
    IL23 Receptor cDNA ORF Clone, Rhesus, C-HA tag CG90123-CY
    IL23 Receptor cDNA ORF Clone, Rhesus, N-HA tag CG90123-NY
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    IL23 Receptor qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    IL23 Receptor cDNA ORF Clone in Cloning Vector, Rat RG80395-G
    IL23 Receptor cDNA ORF Clone, Rat, untagged RG80395-UT
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    IL23 Receptor cDNA ORF Clone, Rat, C-GFPSpark® tag RG80395-ACG
    IL23 Receptor cDNA ORF Clone, Rat, C-OFPSpark® tag RG80395-ACR
    IL23 Receptor cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80395-CF
    IL23 Receptor cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80395-NF
    IL23 Receptor cDNA ORF Clone, Rat, C-His tag RG80395-CH
    IL23 Receptor cDNA ORF Clone, Rat, N-His tag RG80395-NH
    IL23 Receptor cDNA ORF Clone, Rat, C-HA tag RG80395-CY
    IL23 Receptor cDNA ORF Clone, Rat, N-HA tag RG80395-NY
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    IL23 Receptor qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    IL23 Receptor cDNA ORF Clone in Cloning Vector, Mouse MG51293-G
    IL23 Receptor cDNA ORF Clone, Mouse, untagged MG51293-UT
    IL23 Receptor cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51293-ACG
    IL23 Receptor Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51293-ACGLN
    IL23 Receptor cDNA ORF Clone, Mouse, C-OFPSpark® tag MG51293-ACR
    IL23 Receptor cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG51293-CF
    IL23 Receptor cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG51293-NF
    IL23 Receptor cDNA ORF Clone, Mouse, C-His tag MG51293-CH
    IL23 Receptor cDNA ORF Clone, Mouse, N-His tag MG51293-NH
    IL23 Receptor cDNA ORF Clone, Mouse, C-HA tag MG51293-CY
    IL23 Receptor cDNA ORF Clone, Mouse, N-HA tag MG51293-NY
    IL23 Receptor cDNA ORF Clone, Mouse, C-Myc tag MG51293-CM
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    IL23 Receptor qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    IL23 Receptor cDNA ORF Clone in Cloning Vector, Human HG13840-G
    IL23 Receptor cDNA ORF Clone, Human, untagged HG13840-UT
    IL23 Receptor Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG13840-ACGLN
    IL23 Receptor cDNA ORF Clone, Human, C-GFPSpark® tag HG13840-ACG
    IL23 Receptor cDNA ORF Clone, Human, C-OFPSpark® tag HG13840-ACR
    IL23 Receptor cDNA ORF Clone, Human, C-DDK (Flag®) tag HG13840-CF
    IL23 Receptor cDNA ORF Clone, Human, N-DDK (Flag®) tag HG13840-NF
    IL23 Receptor cDNA ORF Clone, Human, C-His tag HG13840-CH
    IL23 Receptor cDNA ORF Clone, Human, N-His tag HG13840-NH
    IL23 Receptor cDNA ORF Clone, Human, C-HA tag HG13840-CY
    IL23 Receptor cDNA ORF Clone, Human, N-HA tag HG13840-NY
    IL23 Receptor cDNA ORF Clone, Human, C-Myc tag HG13840-CM
    IL23 Receptor cDNA ORF Clone, Human, N-Myc tag HG13840-NM
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