IL21 qPCR Primer Pairs, Mouse

Cat: MP200167
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IL21 qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
IL21 qPCR Primer Pairs, Mouse Alternative Names
IL-21 qPCR Primer Pairs, Mouse
IL21 Background Information

IL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. IL21 is expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. It may promote the transition between innate and adaptive immunity. IL-21 has been tried as therapy for alleviating allergic responses. It can significantly decrease pro-inflammatory cytokines produced by T cells in addition to decreasing IgE levels in a mouse model for rhinitis (nasal passage inflammation)

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
interleukin 21
References
  • Coquet JM, et al. (2007) IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production. J Immunol. 178(5):2827-34.
  • Wei L, et al. (2007) IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner. J Biol Chem. 282(48):34605-10.
  • Parrish-Novak J, et al. (2002) Interleukin-21 and the IL-21 receptor: novel effectors of NK and T cell responses. J Leukoc Biol. 72(5):856-63. 4 Kuchen S, et al. (2007) Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration. J Immunol. 179(9):5886-96.
  • IL21 qPCR Primer Pairs, Canine, Related Products

    Product Name Catalog#(PDF)
    IL21 cDNA ORF Clone in Cloning Vector, Canine DG70016-G
    IL21 cDNA ORF Clone, Canine, untagged DG70016-UT
    IL21 cDNA ORF Clone, Canine, C-GFPSpark® tag DG70016-ACG
    IL21 Lentiviral cDNA ORF Clone, Canine, C-GFPSpark® tag DG70016-ACGLN
    IL21 cDNA ORF Clone, Canine, C-OFPSpark® tag DG70016-ACR
    IL21 cDNA ORF Clone, Canine, C-DDK (Flag®) tag DG70016-CF
    IL21 cDNA ORF Clone, Canine, N-DDK (Flag®) tag DG70016-NF
    IL21 cDNA ORF Clone, Canine, C-His tag DG70016-CH
    IL21 cDNA ORF Clone, Canine, N-His tag DG70016-NH
    IL21 cDNA ORF Clone, Canine, C-HA tag DG70016-CY
    IL21 cDNA ORF Clone, Canine, N-HA tag DG70016-NY
    IL21 cDNA ORF Clone, Canine, C-Myc tag DG70016-CM
    IL21 cDNA ORF Clone, Canine, N-Myc tag DG70016-NM

    IL21 qPCR Primer Pairs, Rhesus, Related Products

    Product Name Catalog#(PDF)
    IL21 cDNA ORF Clone in Cloning Vector, Rhesus CG90298-G
    IL21 cDNA ORF Clone, Rhesus, untagged CG90298-UT
    IL21 cDNA ORF Clone, Rhesus, C-GFPSpark® tag CG90298-ACG
    IL21 Lentiviral cDNA ORF Clone, Rhesus, C-GFPSpark® tag CG90298-ACGLN
    IL21 cDNA ORF Clone, Rhesus, C-OFPSpark® tag CG90298-ACR
    IL21 cDNA ORF Clone, Rhesus, C-DDK (Flag®) tag CG90298-CF
    IL21 cDNA ORF Clone, Rhesus, N-DDK (Flag®) tag CG90298-NF
    IL21 cDNA ORF Clone, Rhesus, C-His tag CG90298-CH
    IL21 cDNA ORF Clone, Rhesus, N-His tag CG90298-NH
    IL21 cDNA ORF Clone, Rhesus, C-HA tag CG90298-CY
    IL21 cDNA ORF Clone, Rhesus, N-HA tag CG90298-NY
    IL21 cDNA ORF Clone, Rhesus, C-Myc tag CG90298-CM
    IL21 cDNA ORF Clone, Rhesus, N-Myc tag CG90298-NM

    IL21 qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    IL21 cDNA ORF Clone in Cloning Vector, Rat RG80200-G
    IL21 cDNA ORF Clone, Rat, untagged RG80200-UT
    IL21 cDNA ORF Clone, Rat, C-GFPSpark® tag RG80200-ACG
    IL21 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80200-ACGLN
    IL21 cDNA ORF Clone, Rat, C-OFPSpark® tag RG80200-ACR
    IL21 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80200-CF
    IL21 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80200-NF
    IL21 cDNA ORF Clone, Rat, C-His tag RG80200-CH
    IL21 cDNA ORF Clone, Rat, N-His tag RG80200-NH
    IL21 cDNA ORF Clone, Rat, C-HA tag RG80200-CY
    IL21 cDNA ORF Clone, Rat, N-HA tag RG80200-NY
    IL21 cDNA ORF Clone, Rat, C-Myc tag RG80200-CM
    IL21 cDNA ORF Clone, Rat, N-Myc tag RG80200-NM

    IL21 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    IL21 cDNA ORF Clone in Cloning Vector, Mouse MG50137-M
    IL21 cDNA ORF Clone, Mouse, untagged MG50137-UT
    IL21 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50137-ACGLN
    IL21 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50137-ACG
    IL21 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50137-ACR
    IL21 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50137-CF
    IL21 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50137-NF
    IL21 cDNA ORF Clone, Mouse, C-His tag MG50137-CH
    IL21 cDNA ORF Clone, Mouse, N-His tag MG50137-NH
    IL21 cDNA ORF Clone, Mouse, C-HA tag MG50137-CY
    IL21 cDNA ORF Clone, Mouse, N-HA tag MG50137-NY
    IL21 cDNA ORF Clone, Mouse, C-Myc tag MG50137-CM
    IL21 cDNA ORF Clone, Mouse, N-Myc tag MG50137-NM

    IL21 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    IL21 cDNA ORF Clone in Cloning Vector, Human HG10584-M
    IL21 cDNA ORF Clone, Human, untagged HG10584-UT
    IL21 cDNA ORF Clone, Human, C-GFPSpark® tag HG10584-ACG
    IL21 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10584-ACGLN
    IL21 cDNA ORF Clone, Human, C-OFPSpark® tag HG10584-ACR
    IL21 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10584-CF
    IL21 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10584-NF
    IL21 cDNA ORF Clone, Human, C-His tag HG10584-CH
    IL21 cDNA ORF Clone, Human, N-His tag HG10584-NH
    IL21 cDNA ORF Clone, Human, C-HA tag HG10584-CY
    IL21 cDNA ORF Clone, Human, N-HA tag HG10584-NY
    IL21 cDNA ORF Clone, Human, C-Myc tag HG10584-CM
    IL21 cDNA ORF Clone, Human, N-Myc tag HG10584-NM
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