IL1RA qPCR Primer Pairs, Mouse

Cat: MP201178
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IL1RA qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
IL1RA qPCR Primer Pairs, Mouse Alternative Names
F630041P17Rik qPCR Primer Pairs, Mouse;IL-1ra qPCR Primer Pairs, Mouse
IL1RA Background Information

Interleukin-1 receptor antagonist (IL-1RA) also known as IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. A polymorphism of this protein encoding gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. IL-1RA/IL1RN may inhibit the activity of IL-1 by binding to its receptor and it has no IL-1 like activity. Genetic variation in IL-1RA/IL1RN is associated with susceptibility to microvascular complications of diabetes type 4 (MVCD4). These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. Defects in IL-1RA/IL1RN are the cause of interleukin 1 receptor antagonist deficiency (DIRA) which is also known as deficiency of interleukin 1 receptor antagonist. Autoinflammatory diseases manifest inflammation without evidence of infection, high-titer autoantibodies, or autoreactive T-cells. DIRA is a rare, autosomal recessive, genetic autoinflammatory disease that results in sterile multifocal osteomyelitis, and pustulosis from birth.

Full Name
interleukin 1 receptor antagonist
References
  • Langdahl BL, et al. (2000) Osteoporotic fractures are associated with an 86-base pair repeat polymorphism in the interleukin-1--receptor antagonist gene but not with polymorphisms in the interleukin-1beta gene. J Bone Miner. 15 (3): 402-14.
  • El-Omar EM, et al. (2000) Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature. 404 (6776): 398-402.
  • Steinkasserer A, et al. (1992) The human IL-1 receptor antagonist gene (IL1RN) maps to chromosome 2q14-q21, in the region of the IL-1 alpha and IL-1 beta loci. Genomics. 13 (3): 654-7.
  • IL1RA qPCR Primer Pairs, Ferret, Related Products

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    IL1RA qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
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    IL1RA cDNA ORF Clone, Rat, C-OFPSpark® tag RG80073-ACR
    IL1RA cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80073-CF
    IL1RA cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80073-NF
    IL1RA cDNA ORF Clone, Rat, C-His tag RG80073-CH
    IL1RA cDNA ORF Clone, Rat, N-His tag RG80073-NH
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    IL1RA qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    IL1RA cDNA ORF Clone in Cloning Vector, Mouse MG51300-G
    IL1RA cDNA ORF Clone, Mouse, untagged MG51300-UT
    IL1RA Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51300-ACGLN
    IL1RA cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51300-ACG
    IL1RA cDNA ORF Clone, Mouse, C-OFPSpark® tag MG51300-ACR
    IL1RA cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG51300-CF
    IL1RA cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG51300-NF
    IL1RA cDNA ORF Clone, Mouse, C-His tag MG51300-CH
    IL1RA cDNA ORF Clone, Mouse, N-His tag MG51300-NH
    IL1RA cDNA ORF Clone, Mouse, C-HA tag MG51300-CY
    IL1RA cDNA ORF Clone, Mouse, N-HA tag MG51300-NY
    IL1RA cDNA ORF Clone, Mouse, C-Myc tag MG51300-CM
    IL1RA cDNA ORF Clone, Mouse, N-Myc tag MG51300-NM

    IL1RA qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    IL1RA cDNA ORF Clone in Cloning Vector, Human HG13245-G
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    IL1RA cDNA ORF Clone, Human, untagged HG13245-UT
    IL1RA cDNA ORF Clone, Human, untagged HG10123-UT
    IL1RA cDNA ORF Clone, Human, C-GFPSpark® tag HG10123-ACG
    IL1RA Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10123-ACGLN
    IL1RA Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG13245-ACGLN
    IL1RA cDNA ORF Clone, Human, C-GFPSpark® tag HG13245-ACG
    IL1RA cDNA ORF Clone, Human, C-OFPSpark® tag HG10123-ACR
    IL1RA cDNA ORF Clone, Human, C-OFPSpark® tag HG13245-ACR
    IL1RA cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10123-CF
    IL1RA cDNA ORF Clone, Human, C-DDK (Flag®) tag HG13245-CF
    IL1RA cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10123-NF
    IL1RA cDNA ORF Clone, Human, N-DDK (Flag®) tag HG13245-NF
    IL1RA cDNA ORF Clone, Human, C-His tag HG10123-CH
    IL1RA cDNA ORF Clone, Human, C-His tag HG13245-CH
    IL1RA cDNA ORF Clone, Human, N-His tag HG13245-NH
    IL1RA cDNA ORF Clone, Human, N-His tag HG10123-NH
    IL1RA cDNA ORF Clone, Human, C-HA tag HG13245-CY
    IL1RA cDNA ORF Clone, Human, C-HA tag HG10123-CY
    IL1RA cDNA ORF Clone, Human, N-HA tag HG13245-NY
    IL1RA cDNA ORF Clone, Human, N-HA tag HG10123-NY
    IL1RA cDNA ORF Clone, Human, C-Myc tag HG13245-CM
    IL1RA cDNA ORF Clone, Human, C-Myc tag HG10123-CM
    IL1RA cDNA ORF Clone, Human, N-Myc tag HG10123-NM
    IL1RA cDNA ORF Clone, Human, N-Myc tag HG13245-NM
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