IFNAR1 qPCR Primer Pairs, Mouse

Cat: MP200077
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IFNAR1 qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
IFNAR1 qPCR Primer Pairs, Mouse Alternative Names
CD118 qPCR Primer Pairs, Mouse;Ifar qPCR Primer Pairs, Mouse;Ifnar qPCR Primer Pairs, Mouse;Ifrc qPCR Primer Pairs, Mouse;Infar qPCR Primer Pairs, Mouse
IFNAR1 Background Information

Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. Tyk2 slows down IFNAR1 degradation and that this is due, at least in part, to inhibition of IFNAR1 endocytosis. Mutant versions of IFNAR1, in which Tyr466 is changed to phenylalanine, can act in a dominant negative manner to inhibit phosphorylation of STAT2. These observations are consistent with a model in which IFNAR1 mediates the interaction between JAK kinases and the STAT transcription factors.

Full Name
interferon (alpha, beta and omega) receptor 1
References
  • Yan H, et al. (1996) Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein. EMBO J. 15(5): 1064-74.
  • Richter MF, et al. (1998) Specific contribution of Tyk2 JH regions to the binding and the expression of the interferon alpha/beta receptor component IFNAR1. J Biol Chem. 273(38): 24723-9.
  • Abramovich C, et al. (1997) A protein-arginine methyltransferase binds to the intracytoplasmic domain of the IFNAR1 chain in the type I interferon receptor. EMBO J. 16(2): 260-6.
  • IFNAR1 qPCR Primer Pairs, Rhesus, Related Products

    Product Name Catalog#(PDF)
    IFNAR1 cDNA ORF Clone in Cloning Vector, Rhesus CG90113-G
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    IFNAR1 qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    IFNAR1 cDNA ORF Clone in Cloning Vector, Rat RG80180-G
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    IFNAR1 cDNA ORF Clone, Rat, C-GFPSpark® tag RG80180-ACG
    IFNAR1 cDNA ORF Clone, Rat, C-OFPSpark® tag RG80180-ACR
    IFNAR1 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80180-CF
    IFNAR1 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80180-NF
    IFNAR1 cDNA ORF Clone, Rat, C-His tag RG80180-CH
    IFNAR1 cDNA ORF Clone, Rat, N-His tag RG80180-NH
    IFNAR1 cDNA ORF Clone, Rat, C-HA tag RG80180-CY
    IFNAR1 cDNA ORF Clone, Rat, N-HA tag RG80180-NY
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    IFNAR1 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    IFNAR1 cDNA ORF Clone in Cloning Vector, Mouse MG50469-M
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    IFNAR1 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50469-ACGLN
    IFNAR1 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50469-ACR
    IFNAR1 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50469-CF
    IFNAR1 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50469-NF
    IFNAR1 cDNA ORF Clone, Mouse, C-His tag MG50469-CH
    IFNAR1 cDNA ORF Clone, Mouse, N-His tag MG50469-NH
    IFNAR1 cDNA ORF Clone, Mouse, C-HA tag MG50469-CY
    IFNAR1 cDNA ORF Clone, Mouse, N-HA tag MG50469-NY
    IFNAR1 cDNA ORF Clone, Mouse, C-Myc tag MG50469-CM
    IFNAR1 cDNA ORF Clone, Mouse, N-Myc tag MG50469-NM

    IFNAR1 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
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