***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***
HGF activator (HGFA) is a serum-derived serine protease and belongs to the peptidase family S1.HGFA is responsible for the conversion of hepatocyte growth factor (HGF), from the inactive single-chain precursor to the active heterodimeric form, which is a potent mitogen, motogen, and morphogen for liver cells, epithelial cells, and endothelial cells. HGFA is synthesized and secreted by the liver and circulates in the plasma as an inactive single-chain zymogen in normal states. The zymogen is cleaved by thrombin or thermolysin through the endoproteolytic process and forms an active heterodimer linked by a disulfide bond. In turn, the active protease can be inhibited by HGFA inhibitors (HAIs) including HAI-1 and HAI-2. In addition, the HGFA zymogen acquires a strong affinity upon activation and thus may ensure the local action in tissue regeneration in liver, kidney and skin. It has been reported that activation of HGF is a critical limiting step in the HGF/SF-induced signaling pathway mediated by Met, and accordingly, aberrant expression of HGFA is implicated in tumorigenesis and progression.
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HGF Activator qPCR Primer Pairs, Human, Related Products
|HGF Activator cDNA ORF Clone in Cloning Vector, Human||HG10329-M|
|HGF Activator cDNA ORF Clone, Human, untagged||HG10329-UT|
|HGF Activator cDNA ORF Clone, Human, C-GFPSpark® tag||HG10329-ACG|
|HGF Activator Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag||HG10329-ACGLN|
|HGF Activator cDNA ORF Clone, Human, C-OFPSpark® tag||HG10329-ACR|
|HGF Activator cDNA ORF Clone, Human, C-DDK (Flag®) tag||HG10329-CF|
|HGF Activator cDNA ORF Clone, Human, N-DDK (Flag®) tag||HG10329-NF|
|HGF Activator cDNA ORF Clone, Human, C-His tag||HG10329-CH|
|HGF Activator cDNA ORF Clone, Human, N-His tag||HG10329-NH|
|HGF Activator cDNA ORF Clone, Human, C-HA tag||HG10329-CY|
|HGF Activator cDNA ORF Clone, Human, N-HA tag||HG10329-NY|
|HGF Activator cDNA ORF Clone, Human, C-Myc tag||HG10329-CM|
|HGF Activator cDNA ORF Clone, Human, N-Myc tag||HG10329-NM|