TIM-1 cDNA ORF Clone, Mouse, untagged

Cat: MG50321-UT
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TIM-1 cDNA ORF Clone, Mouse, untagged General Information
Gene
Species
Mouse
NCBI Ref Seq
RefSeq ORF Size
918 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Description
Full length Clone DNA of Mouse hepatitis A virus cellular receptor 1.
Plasmid
Promoter
Enhanced CMV promoter
Vector
pCMV3-untagged
Restriction Sites
KpnI + XbaI (6.1kb + 0.92kb)
Sequencing Primers
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Ampicillin
Antibiotic in Mammalian cell
Hygromycin
Application
Stable or Transient mammalian expression
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
TIM-1 cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

TIM-1 cDNA ORF Clone, Mouse, untagged Alternative Names
AI503787 cDNA ORF Clone, Mouse;KIM-1 cDNA ORF Clone, Mouse;TIM-1 cDNA ORF Clone, Mouse;Tim1 cDNA ORF Clone, Mouse;Timd1 cDNA ORF Clone, Mouse
TIM-1 Background Information

HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â…  integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.

Full Name
hepatitis A virus cellular receptor 1
References
  • Tami C, et al. (2007) Immunoglobulin A (IgA) is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus-receptor interactions. J Virol. 81(7): 3437-46.
  • Rees AJ, et al. (2008) Kim-1/Tim-1: from biomarker to therapeutic target? Nephrol Dial Transplant. 23(11): 3394-6.
  • Chaturvedi S, et al. (2009) Assay validation for KIM-1: human urinary renal dysfunction biomarker. Int J Biol Sci. 5(2): 128-34.
  • TIM-1 cDNA ORF Clone, Canine, Related Products

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    TIM-1 cDNA ORF Clone, Rat, Related Products

    Product Name Catalog#(PDF)
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    TIM-1 cDNA ORF Clone, Mouse, Related Products

    Product Name Catalog#(PDF)
    TIM-1 cDNA ORF Clone in Cloning Vector, Mouse MG50321-M
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    TIM-1 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50321-NF
    TIM-1 cDNA ORF Clone, Mouse, C-His tag MG50321-CH
    TIM-1 cDNA ORF Clone, Mouse, N-His tag MG50321-NH
    TIM-1 cDNA ORF Clone, Mouse, C-HA tag MG50321-CY
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    TIM-1 cDNA ORF Clone, Mouse, N-Myc tag MG50321-NM
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    TIM-1 cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
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    TIM-1 cDNA ORF Clone, Human, N-HA tag HG11051-NY
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    info info
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