Factor VII qPCR Primer Pairs, Mouse

Cat: MP200034
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Factor VII qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
Factor VII qPCR Primer Pairs, Mouse Alternative Names
AI132620 qPCR Primer Pairs, Mouse;Cf7 qPCR Primer Pairs, Mouse;FVII qPCR Primer Pairs, Mouse
Factor VII Background Information

Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is an enzyme of the serine protease class, and Factor VII (FVII) deficiency is the most frequent among rare congenital bleeding disorders. Factor VII contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one peptidase S1 domain. The main role of factor VII is to initiate the process of coagulation in conjunction with tissue factor (TF). Tissue factor is found on the outside of blood vessels, normally not exposed to the blood stream. The action of the Factor VII is impeded by tissue factor pathway inhibitor (TFPI), which is released almost immediately after initiation of coagulation. Factor VII is vitamin K dependent and is produced in the liver. Upon vessel injury, tissue factor is exposed to the blood and circulating Factor VII. Once bound to TF, FVII is activated to FVIIa by different proteases, among which are thrombin (factor IIa), factor Xa, IXa, XIIa, and the FVIIa-TF complex itself. Recombinant activated factor VII (rFVIIa) is a haemostatic agent, which was originally developed for the treatment of haemophilia patients with inhibitors against factor FVIII or FIX. FVIIa binds specifically to endothelial protein C receptor (EPCR), a known cellular receptor for protein C and activated protein C, on the endothelium. rFVIIa is a novel hemostatic agent, originally developed for the treatment of hemorrhage in hemophiliacs with inhibitors, which has been successfully used recently in an increasing number of nonhemophilic bleeding conditions.

Full Name
coagulation factor VII (serum prothrombin conversion accelerator)
References
  • Franchini M, et al. (2007) Potential role of recombinant activated factor VII for the treatment of severe bleeding associated with disseminated intravascular coagulation: a systematic review. Blood Coagul Fibrinolysis. 18(7): 589-93.
  • Lapecorella M, et al. (2008) Factor VII deficiency: defining the clinical picture and optimizing therapeutic options. Haemophilia. 14(6): 1170-5.
  • Grottke O, et al. (2010) Activated recombinant factor VII (rFVIIa). Best Pract Res Clin Anaesthesiol. 24(1): 95-106.
  • Factor VII qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    Factor VII cDNA ORF Clone in Cloning Vector, Mouse MG50034-M
    Factor VII cDNA ORF Clone, Mouse, untagged MG50034-UT
    Factor VII Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50034-ACGLN
    Factor VII cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50034-ACG
    Factor VII cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50034-ACR
    Factor VII cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50034-CF
    Factor VII cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50034-NF
    Factor VII cDNA ORF Clone, Mouse, C-His tag MG50034-CH
    Factor VII cDNA ORF Clone, Mouse, N-His tag MG50034-NH
    Factor VII cDNA ORF Clone, Mouse, C-HA tag MG50034-CY
    Factor VII cDNA ORF Clone, Mouse, N-HA tag MG50034-NY
    Factor VII cDNA ORF Clone, Mouse, C-Myc tag MG50034-CM
    Factor VII cDNA ORF Clone, Mouse, N-Myc tag MG50034-NM

    Factor VII qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    Factor VII cDNA ORF Clone in Cloning Vector, Human HG14137-G
    Factor VII cDNA ORF Clone in Cloning Vector, Human HG11506-M
    Factor VII cDNA ORF Clone, Human, untagged HG14137-UT
    Factor VII cDNA ORF Clone, Human, untagged HG11506-UT
    Factor VII Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG14137-ACGLN
    Factor VII cDNA ORF Clone, Human, C-GFPSpark® tag HG11506-ACG
    Factor VII cDNA ORF Clone, Human, C-GFPSpark® tag HG14137-ACG
    Factor VII Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG11506-ACGLN
    Factor VII cDNA ORF Clone, Human, C-OFPSpark® tag HG14137-ACR
    Factor VII cDNA ORF Clone, Human, C-OFPSpark® tag HG11506-ACR
    Factor VII cDNA ORF Clone, Human, C-DDK (Flag®) tag HG14137-CF
    Factor VII cDNA ORF Clone, Human, C-DDK (Flag®) tag HG11506-CF
    Factor VII cDNA ORF Clone, Human, N-DDK (Flag®) tag HG14137-NF
    Factor VII cDNA ORF Clone, Human, N-DDK (Flag®) tag HG11506-NF
    Factor VII cDNA ORF Clone, Human, C-His tag HG14137-CH
    Factor VII cDNA ORF Clone, Human, C-His tag HG11506-CH
    Factor VII cDNA ORF Clone, Human, N-His tag HG11506-NH
    Factor VII cDNA ORF Clone, Human, N-His tag HG14137-NH
    Factor VII cDNA ORF Clone, Human, C-HA tag HG11506-CY
    Factor VII cDNA ORF Clone, Human, C-HA tag HG14137-CY
    Factor VII cDNA ORF Clone, Human, N-HA tag HG14137-NY
    Factor VII cDNA ORF Clone, Human, N-HA tag HG11506-NY
    Factor VII cDNA ORF Clone, Human, C-Myc tag HG14137-CM
    Factor VII cDNA ORF Clone, Human, C-Myc tag HG11506-CM
    Factor VII cDNA ORF Clone, Human, N-Myc tag HG11506-NM
    Factor VII cDNA ORF Clone, Human, N-Myc tag HG14137-NM
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