Cathepsin A qPCR Primer Pairs, Mouse

Cat: MP200067
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All Cathepsin A Reagents
CRO Services
Product recommended

All Cathepsin A Reagents
Cathepsin A qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
Cathepsin A qPCR Primer Pairs, Mouse Alternative Names
AU019505 qPCR Primer Pairs, Mouse;PPCA qPCR Primer Pairs, Mouse;Ppgb qPCR Primer Pairs, Mouse
Cathepsin A Background Information

Lysosomal carboxypeptidase, cathepsin A (protective protein, CathA), is a component of the lysosomal multienzyme complex along with beta-galactosidase (GAL) and sialidase Neu1, where it activates Neu1 and protects GAL and Neu1 against the rapid proteolytic degradation. Cathepsin A is a multicatalytic enzyme with deamidase and esterase in addition to carboxypeptidase activities. It was recently identified in human platelets as deamidase. In vitro, it hydrolyzes a variety of bioactive peptide hormones including tachykinins, suggesting that extralysosomal cathepsin A plays a role in regulation of bioactive peptide functions. It is a member of the alpha/beta hydrolase fold family and has been suggested to share a common ancestral relationship with other alpha/beta hydrolase fold enzymes, such as cholinesterases. Cathepsin A defects are linked to multiple forms of Galactosialidosis with a combined secondary deficiency of beta-galactosidase and neuraminidase. Cathepsin A is a key molecule in the onset of galactosialidosis and also highlight the therapeutic acts in vivo as an endothelin-1-inactivating enzyme and strongly confirm a crucial role of this enzyme in effective elastic fiber formation.

Full Name
cathepsin A
References
  • Hiraiwa M. (1999) Cathepsin A/protective protein: an unusual lysosomal multifunctional protein. Cell Mol Life Sci. 56(11-12): 894-907.
  • Yoshida T, et al. (2006) Comparative analysis of binding energy of chymostatin with human cathepsin A and its homologous proteins by molecular orbital calculation. J Chem Inf Model. 46(5): 2093-103.
  • Seyrantepe V, et al. (2008) Enzymatic activity of lysosomal carboxypeptidase (cathepsin) A is required for proper elastic fiber formation and inactivation of endothelin-1. Circulation. 117(15): 1973-81.
  • Cathepsin A qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    Cathepsin A cDNA ORF Clone in Cloning Vector, Rat RG87436-U
    Cathepsin A Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG87436-ACGLN

    Cathepsin A qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    Cathepsin A cDNA ORF Clone in Cloning Vector, Mouse MG50348-M
    Cathepsin A cDNA ORF Clone, Mouse, untagged MG50348-UT
    Cathepsin A cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50348-ACG
    Cathepsin A Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50348-ACGLN
    Cathepsin A cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50348-ACR
    Cathepsin A cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50348-CF
    Cathepsin A cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50348-NF
    Cathepsin A cDNA ORF Clone, Mouse, C-His tag MG50348-CH
    Cathepsin A cDNA ORF Clone, Mouse, N-His tag MG50348-NH
    Cathepsin A cDNA ORF Clone, Mouse, C-HA tag MG50348-CY
    Cathepsin A cDNA ORF Clone, Mouse, N-HA tag MG50348-NY
    Cathepsin A cDNA ORF Clone, Mouse, C-Myc tag MG50348-CM
    Cathepsin A cDNA ORF Clone, Mouse, N-Myc tag MG50348-NM

    Cathepsin A qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    Cathepsin A cDNA ORF Clone in Cloning Vector, Human HG10482-U
    Cathepsin A cDNA ORF Clone, Human, untagged HG10482-UT
    Cathepsin A Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10482-ACGLN
    Cathepsin A cDNA ORF Clone, Human, C-GFPSpark® tag HG10482-ACG
    Cathepsin A cDNA ORF Clone, Human, C-OFPSpark® tag HG10482-ACR
    Cathepsin A cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10482-CF
    Cathepsin A cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10482-NF
    Cathepsin A cDNA ORF Clone, Human, C-His tag HG10482-CH
    Cathepsin A cDNA ORF Clone, Human, N-His tag HG10482-NH
    Cathepsin A cDNA ORF Clone, Human, C-HA tag HG10482-CY
    Cathepsin A cDNA ORF Clone, Human, N-HA tag HG10482-NY
    Cathepsin A cDNA ORF Clone, Human, C-Myc tag HG10482-CM
    Cathepsin A cDNA ORF Clone, Human, N-Myc tag HG10482-NM
    info info
    添加购物车成功! 添加购物车失败!