|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Mouse CNTN4 ORF mammalian expression plasmid, C-GFPSpark tag||MG50570-ACG|
|Mouse CNTN4 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50570-ACR|
|Mouse CNTN4 ORF mammalian expression plasmid, C-Flag tag||MG50570-CF|
|Mouse CNTN4 ORF mammalian expression plasmid, C-His tag||MG50570-CH|
|Mouse CNTN4 ORF mammalian expression plasmid, C-Myc tag||MG50570-CM|
|Mouse CNTN4 ORF mammalian expression plasmid, C-HA tag||MG50570-CY|
|Mouse CNTN4 Gene cDNA clone plasmid||MG50570-M|
|Mouse CNTN4 ORF mammalian expression plasmid, N-Flag tag||MG50570-NF|
|Mouse CNTN4 ORF mammalian expression plasmid, N-His tag||MG50570-NH|
|Mouse CNTN4 ORF mammalian expression plasmid, N-Myc tag||MG50570-NM|
|Mouse CNTN4 ORF mammalian expression plasmid, N-HA tag||MG50570-NY|
|Mouse CNTN4 natural ORF mammalian expression plasmid||MG50570-UT|
|Learn more about expression Vectors|
Contactin-4, abbreviated as CNTN4, is a brain-derived protein belonging to the immunoglobulin superfamily. It has been found high expression in testes, thyroid, small intestine, uterus and brain. This protein is an neuronal membrane protein that functions as an glycosylphosphatidylinositol- anchored cell adhesion molecule. Contactin-4 is considered as a candidate protein responsible for the differentiation potential of human neuroblastoma cells and it has been implicated in some cases of autism and spinocerebellar ataxia type 16. Studies of the cantactin family have revealed a complex pattern of hemophilic and heterophilic interactions that are required for axon growth and pathfinding. Such studies demonstrate that these essential functions are mediated by the combination and juxtaposition of multiple Ig and FNIII domains. Second, these neuronal adhesion molecules demonstrate highly regulated temporal and spatial expression patterns in the CNS. For this reason, the disruption of the regulatory region of the predominant brain-expressed isoform reasonable would be expected to have significant functional consequences.