CD86 qPCR Primer Pairs, Mouse

Cat: MP200099
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CD86 qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
CD86 qPCR Primer Pairs, Mouse Alternative Names
B7 qPCR Primer Pairs, Mouse;B7-2 qPCR Primer Pairs, Mouse;B7.2 qPCR Primer Pairs, Mouse;B70 qPCR Primer Pairs, Mouse;Cd28l2 qPCR Primer Pairs, Mouse;CLS1 qPCR Primer Pairs, Mouse;ETC-1 qPCR Primer Pairs, Mouse;Ly-58 qPCR Primer Pairs, Mouse;Ly58 qPCR Primer Pairs, Mouse;MB7 qPCR Primer Pairs, Mouse;MB7-2 qPCR Primer Pairs, Mouse;TS/A-2 qPCR Primer Pairs, Mouse
CD86 Background Information

CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. Recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.

Immune Checkpoint
Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: IP Antibodies   Immune Checkpoint Detection: FCM Antibodies   Immune Checkpoint Detection: WB Antibodies
Immune Checkpoint Proteins
Immune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets

Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
CD86 antigen
References
  • Chen YQ, et al. (2006) CD28/CTLA-4--CD80/CD86 and ICOS--B7RP-1 costimulatory pathway in bronchial asthma. Allergy. 61(1): 15-26.
  • Rau FC, et al. (2009) B7-1/2 (CD80/CD86) direct signaling to B cells enhances IgG secretion. J Immunol. 183(12): 7661-71.
  • Dai ZS, et al. (2009) Defective expression and modulation of B7-2/CD86 on B cells in B cell chronic lymphocytic leukemia. Int J Hematol. 89(5): 656-63.
  • CD86 qPCR Primer Pairs, Rhesus, Related Products

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    CD86 cDNA ORF Clone in Cloning Vector, Rhesus CG90270-G
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    CD86 qPCR Primer Pairs, Rat, Related Products

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    CD86 cDNA ORF Clone in Cloning Vector, Rat RG80025-M
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    CD86 qPCR Primer Pairs, Mouse, Related Products

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    CD86 cDNA ORF Clone in Cloning Vector, Mouse MG50068-M
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    CD86 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50068-NF
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    CD86 cDNA ORF Clone, Mouse, N-His tag MG50068-NH
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    CD86 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
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    CD86 cDNA ORF Clone, Human, C-His tag HG10699-CH
    CD86 cDNA ORF Clone, Human, N-His tag HG10699-NH
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    CD86 cDNA ORF Clone, Human, C-Myc tag HG10699-CM
    CD86 cDNA ORF Clone, Human, N-Myc tag HG10699-NM
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