CD200 qPCR Primer Pairs, Mouse

Cat: MP200105
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CD200 qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
CD200 qPCR Primer Pairs, Mouse Alternative Names
Mox2 qPCR Primer Pairs, Mouse;OX2 qPCR Primer Pairs, Mouse
CD200 Background Information

CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through the CD200:CD200R axis have been shown to play an important role in the regulation of anti-tumor immunity, and overexpression of CD200 has been reported in a number of malignancies, including CLL, as well as on cancer stem cells. The role of CD200-CD200R signaling in immune regulation of the central nervous system has become a popular field of research in recent years. Many studies have shown that there is a close correlation between CD200-CD200R, microglia activation, and Parkinson's disease (PD). The ability of CD200 to suppress myeloid cell activation is critical for maintaining normal tissue homeostasis but may also enhance the survival of migratory neoplastic cells. CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 has been characterized as an important immunoregulatory molecule, increased expression of which can lead to decreased transplant rejection, autoimmunity, and allergic disease. Elevated CD200 expression has been reported to be associated with poor prognosis in a number of human malignancies. In addition, CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
Cd200 molecule
References
  • Minas K, et al. (2006) Is the CD200/CD200 receptor interaction more than just a myeloid cell inhibitory signal? Crit Rev Immunol. 26(3): 213-30.
  • Wang XJ, et al. (2007) CD200-CD200R regulation of microglia activation in the pathogenesis of Parkinson's disease. J Neuroimmune Pharmacol. 2(3): 259-64.
  • Wong KK, et al. (2010) The role of CD200 in immunity to B cell lymphoma. J Leukoc Biol. 88(2): 361-72.
  • CD200 qPCR Primer Pairs, Rhesus, Related Products

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    CD200 qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
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    CD200 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    CD200 cDNA ORF Clone in Cloning Vector, Mouse MG50074-M
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    CD200 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50074-ACGLN
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    CD200 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50074-CF
    CD200 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50074-NF
    CD200 cDNA ORF Clone, Mouse, C-His tag MG50074-CH
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    CD200 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    CD200 cDNA ORF Clone in Cloning Vector, Human HG10886-M
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    CD200 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10886-ACGLN
    CD200 cDNA ORF Clone, Human, C-OFPSpark® tag HG10886-ACR
    CD200 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10886-CF
    CD200 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10886-NF
    CD200 cDNA ORF Clone, Human, C-His tag HG10886-CH
    CD200 cDNA ORF Clone, Human, N-His tag HG10886-NH
    CD200 cDNA ORF Clone, Human, C-HA tag HG10886-CY
    CD200 cDNA ORF Clone, Human, N-HA tag HG10886-NY
    CD200 cDNA ORF Clone, Human, C-Myc tag HG10886-CM
    CD200 cDNA ORF Clone, Human, N-Myc tag HG10886-NM
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