CCL5 qPCR Primer Pairs, Mouse

Cat: MP200022
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CCL5 qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
CCL5 qPCR Primer Pairs, Mouse Alternative Names
MuRantes qPCR Primer Pairs, Mouse;RANTES qPCR Primer Pairs, Mouse;Scya5 qPCR Primer Pairs, Mouse;SISd qPCR Primer Pairs, Mouse;TCP228 qPCR Primer Pairs, Mouse
CCL5 Background Information

Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 5(CCL5) is chemotactic for T cells, basophils and eosinophils. Chemokin ligand 5(CCL5) has been considered a HIV-supressor secreted by CD8+ T cells and other immune cells. Chemokin ligand 5(CCL5) is a key to activating recruit leukocytes into inflammatory sites and in the presence of particular cytokines released by T cells, it can change the NK cells into CHAK cells.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
chemokine (C-C motif) ligand 5
References
  • Laing KJ, et al. (2004) Chemokines. Developmental and comparative immunology. 28(5): 443-60.
  • Cocchi F, et al. (1995) Identification of RANTES, MIP-1a, and MIP-1b as the major HIV-suppressive factor produced by CD8+ T cells. Science. 270 (5243): 1811-5.
  • Vangelista L, et al. (2010) Engineering of Lactobacillus jensenii to secrete RANTES and a CCR5 antagonist analogue as live HIV-1 blockers. Antimicrob. Agents Chemother. 54 (7): 2994-3001.
  • Maghazachi AA, et al. (1996) CC chemokines induce the generation of killer cells from CD56+ cells. Eur. J. Immunol. 26 (2): 315-9.
  • CCL5 qPCR Primer Pairs, Canine, Related Products

    Product Name Catalog#(PDF)
    CCL5 cDNA ORF Clone in Cloning Vector, Canine DG70007-M
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    CCL5 cDNA ORF Clone, Canine, C-DDK (Flag®) tag DG70007-CF
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    CCL5 cDNA ORF Clone, Canine, N-His tag DG70007-NH
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    CCL5 qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    CCL5 cDNA ORF Clone in Cloning Vector, Rat RG80038-M
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    CCL5 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80038-ACGLN
    CCL5 cDNA ORF Clone, Rat, C-OFPSpark® tag RG80038-ACR
    CCL5 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80038-CF
    CCL5 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80038-NF
    CCL5 cDNA ORF Clone, Rat, C-His tag RG80038-CH
    CCL5 cDNA ORF Clone, Rat, N-His tag RG80038-NH
    CCL5 cDNA ORF Clone, Rat, C-HA tag RG80038-CY
    CCL5 cDNA ORF Clone, Rat, N-HA tag RG80038-NY
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    CCL5 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    CCL5 cDNA ORF Clone in Cloning Vector, Mouse MG50022-M
    CCL5 cDNA ORF Clone, Mouse, untagged MG50022-UT
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    CCL5 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50022-ACGLN
    CCL5 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50022-ACR
    CCL5 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50022-CF
    CCL5 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50022-NF
    CCL5 cDNA ORF Clone, Mouse, C-His tag MG50022-CH
    CCL5 cDNA ORF Clone, Mouse, N-His tag MG50022-NH
    CCL5 cDNA ORF Clone, Mouse, C-HA tag MG50022-CY
    CCL5 cDNA ORF Clone, Mouse, N-HA tag MG50022-NY
    CCL5 cDNA ORF Clone, Mouse, C-Myc tag MG50022-CM
    CCL5 cDNA ORF Clone, Mouse, N-Myc tag MG50022-NM

    CCL5 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    CCL5 cDNA ORF Clone in Cloning Vector, Human HG10900-M
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    CCL5 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10900-ACGLN
    CCL5 cDNA ORF Clone, Human, C-OFPSpark® tag HG10900-ACR
    CCL5 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10900-CF
    CCL5 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10900-NF
    CCL5 cDNA ORF Clone, Human, C-His tag HG10900-CH
    CCL5 cDNA ORF Clone, Human, N-His tag HG10900-NH
    CCL5 cDNA ORF Clone, Human, C-HA tag HG10900-CY
    CCL5 cDNA ORF Clone, Human, N-HA tag HG10900-NY
    CCL5 cDNA ORF Clone, Human, C-Myc tag HG10900-CM
    CCL5 cDNA ORF Clone, Human, N-Myc tag HG10900-NM
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