BID cDNA ORF Clone, Mouse, N-Myc tag

Cat: MG50351-NM
Contact us:
+86-400-890-9989
order@sinobiological.com
Distributors
All BID Reagents
CRO Services
Product recommended

All BID Reagents
BID cDNA ORF Clone, Mouse, N-Myc tag General Information
Gene
Species
Mouse
NCBI Ref Seq
RefSeq ORF Size
588 bp
Description
Full length Clone DNA of Mouse BH3 interacting domain death agonist with N terminal Myc tag.
Plasmid
Promoter
Enhanced CMV promoter
Vector
pCMV3-N-Myc
Tag Sequence
Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
Sequencing Primers
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Kanamycin
Antibiotic in Mammalian cell
Hygromycin
Application
Stable or Transient mammalian expression
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

BID cDNA ORF Clone, Mouse, N-Myc tag Alternative Names
2700049M22Rik cDNA ORF Clone, Mouse;AI875481 cDNA ORF Clone, Mouse;AU022477 cDNA ORF Clone, Mouse
BID Background Information

The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains only the BH3 domain, and is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. BID is important to cell death mediated by these proteases and thus is the sentinel to protease-mediated death signals. Recent studies further indicate that Bid may be more than just a killer molecule, it could be also involved in the maintenance of genomic stability by engaging at mitosis checkpoint. BID is an integrating key regulator of the intrinsic death pathway that amplifies caspase-dependent and caspase-independent execution of neuronal apoptosis. Therefore pharmacological inhibition of BID provides a promising therapeutic strategy in neurological diseases where programmed cell death is prominent. BID is activated by Caspase 8 in response to Fas/TNF-R1 death receptor activation. Activated BID is translocated to mitochondria and induces cytochrome c release, which in turn activates downstream caspases. BID action has been proposed to involve the mitochondrial re-location of its truncated form, tBid, to facilitate the release of apoptogenic proteins like cytochrome c.

Full Name
BH3 interacting domain death agonist
References
  • Gross A. (2006) BID as a double agent in cell life and death. Cell Cycle. 5(6): 582-4.
  • Yin XM. (2007) Bid, a BH3-only multi-functional molecule, is at the cross road of life and death. Gene. 369: 7-19.
  • Esposti MD. (2002) The roles of Bid. Apoptosis. 7(5): 433-40.
  • Yin XM. (2000) Signal transduction mediated by Bid, a pro-death Bcl-2 family proteins, connects the death receptor and mitochondria apoptosis pathways. Cell Res. 10(3): 161-7.
  • Yin XM. (2000) Bid, a critical mediator for apoptosis induced by the activation of Fas/TNF-R1 death receptors in hepatocytes. J Mol Med. 78(4): 203-11.
  • BID cDNA ORF Clone, Mouse, Related Products

    Product Name Catalog#(PDF)
    BID cDNA ORF Clone in Cloning Vector, Mouse MG50351-M
    BID cDNA ORF Clone, Mouse, untagged MG50351-UT
    BID cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50351-ACG
    BID Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50351-ACGLN
    BID cDNA ORF Clone, Mouse, N-GFPSpark® tag MG50351-ANG
    BID cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50351-ACR
    BID cDNA ORF Clone, Mouse, N-OFPSpark® tag MG50351-ANR
    BID cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50351-CF
    BID cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50351-NF
    BID cDNA ORF Clone, Mouse, C-His tag MG50351-CH
    BID cDNA ORF Clone, Mouse, N-His tag MG50351-NH
    BID cDNA ORF Clone, Mouse, C-HA tag MG50351-CY
    BID cDNA ORF Clone, Mouse, N-HA tag MG50351-NY
    BID cDNA ORF Clone, Mouse, C-Myc tag MG50351-CM
    BID qPCR Primer Pairs, Mouse MP200372

    BID cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
    BID cDNA ORF Clone in Cloning Vector, Human HG10468-M
    BID cDNA ORF Clone, Human, untagged HG10468-UT
    BID Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10468-ACGLN
    BID cDNA ORF Clone, Human, C-GFPSpark® tag HG10468-ACG
    BID cDNA ORF Clone, Human, N-GFPSpark® tag HG10468-ANG
    BID cDNA ORF Clone, Human, C-OFPSpark® tag HG10468-ACR
    BID cDNA ORF Clone, Human, N-OFPSpark® tag HG10468-ANR
    BID cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10468-CF
    BID cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10468-NF
    BID cDNA ORF Clone, Human, C-His tag HG10468-CH
    BID cDNA ORF Clone, Human, N-His tag HG10468-NH
    BID cDNA ORF Clone, Human, C-HA tag HG10468-CY
    BID cDNA ORF Clone, Human, N-HA tag HG10468-NY
    BID cDNA ORF Clone, Human, C-Myc tag HG10468-CM
    BID cDNA ORF Clone, Human, N-Myc tag HG10468-NM
    BID qPCR Primer Pairs, Human HP100042
    info info
    添加购物车成功! 添加购物车失败!