Monoclonal Antibody (Mab) Engineering: Chimeric Antibody

Advanced Technology & Experienced Production Engineers at Your Service

Excellent Antibody Production Services

Professional Project Management           • Track Records & Service Capacity

Multiple Species Combination

 • Variable region: human, mouse, rat, canine, rhesus, chicken, rabbit, camel
 • Constant region: human, mouse, rat, canine, rhesus, rabbit
 • Multiple constant type:
   a) Antibody classes: IgG, IgM, IgA, IgE
   b) Isotypes: IgG1, IgG2, IgG3, IgG4 (IgG1, IgG2a, IgG2b, IgG2c, IgG3), kappa, lambda
   c) Allotypes: G1m(3), G1m(1,3), G1m(17), G3m(b), G3m(g) etc km1, km1,2, km3

 

Technology:

Chimeric antibody design, Codon optimization, Expression vector construction, Transient transfection, Serum-free cell culture, affinity purification

Host Cells:

HEK293 or CHO cell

Timeline:

4-8 weeks from gene sequence to antibody delivery
 • 1 weeks for gene synthesis
 • 1-2 weeks for vector construction and plasmid production
 • 2-5 weeks for transient transfection, antibody purification, QC testing

Deliverable:

purified antibodies (quantities to be specified by customer) and/or antibody DNA sequence in commercial expression vector

Quality Specification:

>95% antibody purity by SDS page (standard)
endotoxin and/or monomer purity specifications can be requested

Applications:

antibody library, antibody engineering

 

Antibody Polishing Services

•   High Monomer Purity Antibody Production

•   Low Endotoxin Antibody Production

•   Low Endotoxin and High Monomer Purity Antibody Production

Antibody Fragment Production Services

•   ScFv Antibody Fragment Production

•   Fab Antibody Production

Antibody Engineering Services

•   Antibody Humanization Engineering Services

•   Antibody Affinity Maturation Engineering Services

Other Antibody Production Related Services

•   Antibody Gene Synthesis

•   Antibody Gene Codon Optimization

•   Antibody Gene Cloning from Hybridoma Cells

 

Your Antibody Discovery & Development Supporting team

What our Customers Say:

Sweden, University Researcher\uFF1AHere is the data about the Ago2 protein I got from you. I am very glad to say that it is highly active, performs very good in in vitro assays and is also stable at 4C for at least for 2 weeks when tested its enzymatic ac

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"