Micromonospora viridifaciens Neuraminidase (NA) Protein

Micromonospora viridifaciens Neuraminidase (NA) Protein Products

Products	Source (CLICK for detailed Info. and Price)	Molecule	Description	Cat No
Protein	M. viridifaciens Neuraminidase (NA), Recombinant Protein	NA	His Tag	11679-V07E

11679-V07E: The specific activity is 10,000 pmoles/min/µg. Measured by its ability to cleave a fluorogenic substrate, 2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid.

Micromonospora viridifaciens Neuraminidase (NA) Related Areas

Enzyme>>Carbohydrate Metabolism Enzymes>>Micromonospora viridifaciens Neuraminidase (NA)/Sialidase

Immunology>>Innate Immunity>>Lysosomal Enzyme>>Micromonospora viridifaciens Neuraminidase (NA)/Sialidase

Micromonospora viridifaciens Neuraminidase (NA) Alternative Names

Neuraminidase, NA, Sialidase, nedA

Micromonospora viridifaciens Neuraminidase (NA) Background

Neuraminidase enzymes are glycoside hydrolase enzymes which cleave the glycosidic linkages of neuraminic acids. It is an enzyme that catalyzes the cleavage of N-acetyl neuraminic acid from mucopolysaccharides. A hereditary deficiency of the enzyme causes sialidosis and is associated with galactogialidosis. It is characterized by mental retardation and skeletal changes, especially dysotosis multiplex. Neuraminidase enzymes are a large family, found in a range of organisms. There are three major classes of neuraminidase enzymes: Viral neuraminidase, Bacterial neuraminidase and Mammalian neuraminidases. The most commonly known neuraminidase is the viral neuraminidase, a drug target for the prevention of influenza infection.

Micromonospora is a genus of bacteria of the family Micromonosporaceae. Micromonospora viridifaciens is one of the Micromonospora species. They are gram-positive, spore-forming, generally aerobic, and form a branched mycelium. Micromonospora viridifaciens Neuraminidase also known as sialidase. To release sialic acids for use as carbon and energy sources for this non-pathogenic bacterium while in pathogenic microorganisms, sialidases have been suggested to be pathogenic factors.

Micromonospora viridifaciens Neuraminidase (NA) Related Studies

Sakurada K, et al. (1992) Cloning, expression, and characterization of the Micromonospora viridifaciens neuraminidase gene in Streptomyces lividans. J Bacteriol. 174: 6896-903.
Gaskell A, et al. (1995) The three domains of a bacterial sialidase: a beta-propeller, an immunoglobulin module and a galactose-binding jelly-roll. Structure. 3: 1197-205.