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Core Management Team

Dr. Daniel I.C. Wang

• Institute Professor from MIT
• Chairman of the Scientific Advisory Board
• Member of National Academy of Engineering,
• American Academy of Arts and Sciences, and Academia Sinica

Dr. Daniel I.C. Wang is an Institute Professor (MIT Highest Honor) at Massachusetts Institute of Technology. He is a member of National Academy of Engineering, American Academy of Arts and Sciences, and Academia Sinica. He was the editor-in-chief for Biotechnology and Bioengineering for more than 10 years. Over 40 years of pioneering and innovative research in the field of biotechnology and biochemical engineering, Prof. Wang has made profound impact on the biotechnology industry scientific research, and education.
Lots of his students have become main technical backbone and senior leadership in the biotechnology and pharmaceutical companies of United States and Europe. His research interests and contribution to the biotech industry include mammalian cell culture, microbial fermentation, protein purification and refolding, bioreactor engineering, production of recombinant proteins, bioprocess monitoring and control, glycoprotein quality, protein stabilization, enzyme technology and cellulosic biomass conversion.
Professor Wang is a patriotic Chinese American, who has been concerned about the development of biotechnology in China, and trained a number of PhDs and senior visiting scholars for China. He served as foreign experts and consultants for Ministry of Science and Technology (China) in the 1980s. He is also engaged as biotechnology strategy consultant of Singapore, and has made important contributions to the development of biotechnology in Singapore.Prof. Wang also received Honorary Professorships from Peking Union Medical College, China, and Zhejiang University, China.

Liangzhi Xie, Ph.D

• Founder, President and CEO
• Professor, Director of Cell Culture R&D Center, Chinese
• Academy of Medical Sciences & Peking Union Medical College
• Expert in 1000-plan program (China)
• Research fellow, Fermentation and cell culture, Merck Co., Inc.
• Sc.D. in chemical engineering from Massachusetts Institute of •Technology

Dr. Xie founded Sino Biological Inc. in 2007 and served as the President and CEO since then. He started the business for producing research reagents and providing CRO services to global pharmaceutical companies.
Dr. Xie began his career as a research fellow at Merck & Company. He has extensive experience in viral vaccine development. He worked on viral vaccine process development and cGMP manufacturing for three US FDA approved products (Varicella®, Zostervax®, and ProQuad®). He also led the cell culture and viral vaccine process development and cGMP clinical production for Merck’s adenovirus based HIV vaccine and helped to develop by far the largest scale (2000L) of human viral vaccine process under serum-free condition in stirred-tank bioreactors.Dr. Xie obtained his doctor degree from the biotechnology process engineering center at Massachusetts Institute of Technology under the supervision of Prof. Daniel I.C. Wang.

Yang Wang, Ph.D

• Senior vice president, quality control
• Expert in 1000-plan program (China)
• Deputy director of Cell Culture R&D Center, Chinese Academy of Medical Sciences & Peking Union Medical College
• Associate director and department head, Department of biologics analytical development, Merck & Co., Inc.
• Senior research scientist in Massachusetts Institute of Technology
• Ph. D. in biophysical chemistry from University of Oregon
Dr. Wang joined the company in 2010 as senior vice president. Prior to his current role, he worked for 13 years at Merck & Co., Inc in viral vaccine and antibody drug production. He managed a group of more than 50 people responsible for leading the biologics analytical development efforts supporting all Merck's biologics pipelines. He got involved in leading the development of more than 10 drugs under clinical trials or US FDA approved. He received numerous awards during his work in Merck, including Industrial Biotechnology Award from American Chemical Society for the development of the manufacturing process for Gardasil®.
Dr. Wang earned a PhD in biophysical chemistry from University of Oregon and completed postdoctoral studies at Princeton University. He has authored more than 60 scientific papers.
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400+ R&D team
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