MUC1 (Protein|Antibody|cDNA Clone|ELISA Kit)

All MUC1 reagents are produced in house and quality controlled, including 7 MUC1 Antibody, 26 MUC1 Gene, 3 MUC1 Lysate, 3 MUC1 Protein, 2 MUC1 qPCR. All MUC1 reagents are ready to use.

Recombinant MUC1 proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, C-mouse IgG1-Fc, None.

MUC1 antibodies are validated with different applications, which are WB, ELISA, IP, IHC-P, ICC/IF, IF.

MUC1 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each MUC1 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

MUC1 Protein (3)

Species

MUC1 Protein, Human, Recombinant (Fc Tag)

12123-H02H

Expression host: HEK293 Cells

Human MUC1/Mucin 1/CD227 Protein 9971

MUC1 Protein, Human, Recombinant

12123-HCCH

Expression host: HEK293 Cells

Human MUC1/Mucin 1/CD227 Protein 15100

MUC1 Protein, Human, Recombinant (Fc Tag)

12123-H05H

Expression host: HEK293 Cells

Human MUC1/Mucin 1/CD227 Protein 9972
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MUC1 Antibody (7)

Application Clonality
Host

Anti-MUC1 Antibody

12123-MM05

Specificity: Human

Application: ELISA,IHC-P

Clonality: MAb

Human MUC1/Mucin 1/CD227 Immunohistochemistry(IHC) 16039

Anti-MUC1 Antibody

12123-RP01

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-MUC1 Antibody

102352-T10

Specificity: Mouse

Application: IHC-P,ICC/IF,IF

Clonality: PAb

Mouse MUC1/Mucin 1/CD227 Immunohistochemistry(IHC) 18185

Anti-MUC1 Antibody

12123-T52

Application: WB,ELISA,IP

Clonality: PAb

Human MUC1 Western blot (WB) 22273

Anti-MUC1 Antibody

12123-R003

Specificity: Human

Application: ELISA

Clonality: MAb

Anti-MUC1 Antibody

12123-T16

Application: ELISA

Clonality: PAb

Anti-MUC1 Antibody

12123-T24

Specificity: Human

Application: ELISA,IHC-P

Clonality: PAb

Human MUC1/Mucin 1/CD227 Immunohistochemistry(IHC) 3879
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MUC1 cDNA Clone (26)

Mouse
Human

MUC1 qPCR Primer (2)

MUC1 Lysate (3)

Mucin 1, cell surface associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. MUC-1/CC1/CD227 Exclusively located in the apical domain of the plasma membrane of highly polarized epithelial cells. After endocytosis, internalized and recycled to the cell membrane. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. The alpha subunit has cell adhesive properties. MUC-1/CC1/CD227 Can act both as an adhesion and an anti-adhesion protein. This protein May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. MUC-1/CC1/CD227 participated in modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, MUC-1/CC1/CD227 influences directly or indirectly the Ras/MAPK pathway. MUC-1/CC1/CD227 Promotes tumor progression and regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy
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Antibody
Gene
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