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Rat MSR1 / SCARA1 Protein (Fc Tag)
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Rat MSR1 / SCARA1 Protein (Fc Tag) PDF Download

Catalog   Size (Price) Quantity In Stock Operation
80363-R01H  
YES   
 

Protein Production & Purification Service | Recombinant Cytokines & Growth Factors

Macrophage scavenger receptor 1 Protein Datasheet

 

MSR1 / SCARA1 Protein Price Inquiry ( Available Sizes )

MSR1 / SCARA1 Protein Product Information

Synonym : MSR1
Protein Construction:

A DNA sequence encoding the rat MSR1 (Trp79-Ser454) was expressed, fused  with the Fc region of human IgG1 at the N-terminus.

Source: Rat
Expression Host: Human Cells

MSR1 / SCARA1 Protein QC Testing

Purity: > 95 % as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE

MSR1 / SCARA1 protein

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Glu
Molecular Mass:

The recombinant Rat MSR1/Fc  comprises 636 amino acids and has a predicted molecular mass of 69.2 kDa. The apparent molecular mass of the protein is approximately 89 kDa in SDS-PAGE under reducing conditions.

Formulation: Lyophilized from sterile PBS, pH7.4.
  1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
  2. Please contact us for any concerns or special requirements.

MSR1 / SCARA1 Protein Usage Guide

Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

MSR1 / SCARA1 Protein Related Products & Topics

Related Areas:

Immunology>>Innate Immunity>>Monocyte/Macrophage>>Scavenger Receptor>>MSR1/CD204

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Macrophage Markers>>MSR1/CD204

Proteins:

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
MSR1/CD204/SCARA1 Human MSR1/CD204 Protein, Recombinant 10427-H07H
MSR1/CD204/SCARA1 Mouse MSR1/CD204 Protein, Recombinant 50129-M07H
MSR1/CD204/SCARA1 Rat MSR1 / SCARA1 Protein, Recombinant 80363-R01H

Antibodies:

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
MSR1/CD204/SCARA1
WB, ELISA MSR1/CD204 Antibody, Mouse MAb 10427-MM02
Human
MSR1/CD204/SCARA1
WB, ELISA MSR1/CD204 Antibody, Rabbit MAb 10427-R005
Mouse
MSR1/CD204/SCARA1
WB, ELISA MSR1 / CD204 Antibody 50129-RP01
Mouse
MSR1/CD204/SCARA1
WB, ELISA MSR1 / CD204 Antibody (Antigen Affinity Purified) 50129-RP02
Human
MSR1/CD204/SCARA1
FCM MSR1 / CD204 Antibody ( FITC ) 50129-R004-F

MSR1 / SCARA1 Protein Description

Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD204, MSR1 and SCARA1, is a single-pass type I I membrane protein which contains one collagen-like domain and one SRCR domain. Macrophages are distributed in all peripheral tissues and play a critical role in the first line of the innate immune defenses against bacterial infection by phagocytosis of bacterial pathogens through the macrophage scavenger receptor 1 (MSR1). MSR1 / SCARA1 is one of the membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). MSR1 / SCARA1 is also involved in chronic inflammation which is a risk factor for prostate cancer. MSR1 1 gene was identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer.

References

  1. Wang L. et al., 2003, Nat Genet. 35 (2): 128-9.
  2. Chen Y.C. et al., 2008, Cancer Epidemiol Biomarkers Prev. 17 (4): 1001-3.
  3. Shirato K. et al., 2009, Pflugers Arch. 459 (1): 93-103.
  4. Sun J. et al., 2006, Prostate. 66 (7): 728-37.
 
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"