Anti-CD204 Antibody

Cat: 50129-RP02
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All CD204 Reagents
Anti-CD204 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-CD204 Antibody
Validated applications
ELISA,IHC-P
Species reactivity
Reacts with: Mouse
Specificity
Mouse CD204
Immunogen
Recombinant Mouse MSR1 / CD204 protein (Catalog#50129-M07H)
Preparation
Produced in rabbits immunized with purified, recombinant Mouse MSR1 / CD204 (rM MSR1 / CD204; Catalog#50129-M07H; AAH03814.1; Trp 83-Val 354). MSR1 / CD204 specific IgG was purified by Mouse MSR1 / CD204 affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CD204 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  
IHC-P 1:500-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CD204 Antibody (Rabbit Polyclonal antibody) Images
Mouse MSR1/CD204 Immunohistochemistry(IHC) 3232
Immunochemical staining of mouse MSR1 in mouse liver with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).Positive staining was localized to hepatic sinusoid.
Anti-CD204 Antibody Alternative Names
Anti-MRS-A Antibody;Anti-MSR Antibody;Anti-MSR-A Antibody;Anti-Scara1 Antibody;Anti-Scvr Antibody;Anti-SR-AI Antibody;Anti-SR-AII Antibody
CD204 Background Information

Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD204, MSR1 and SCARA1, is a single-pass type I I membrane protein which contains one collagen-like domain and one SRCR domain. Macrophages are distributed in all peripheral tissues and play a critical role in the first line of the innate immune defenses against bacterial infection by phagocytosis of bacterial pathogens through the macrophage scavenger receptor 1 (MSR1). MSR1 / SCARA1 is one of the membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). MSR1 / SCARA1 is also involved in chronic inflammation which is a risk factor for prostate cancer. MSR1 1 gene was identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer.

Full Name
macrophage scavenger receptor 1
References
  • Wang L. et al., 2003, Nat Genet. 35 (2): 128-9.
  • Chen Y.C. et al., 2008, Cancer Epidemiol Biomarkers Prev. 17 (4): 1001-3.
  • Shirato K. et al., 2009, Pflugers Arch. 459 (1): 93-103.
  • Sun J. et al., 2006, Prostate. 66 (7): 728-37.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CD204 Antibody Rabbit Monoclonal IHC-P,FCM,ICC/IF,IF 50129-R004
    Anti-CD204 Antibody (FITC) Rabbit Monoclonal FCM 50129-R004-F
    Anti-CD204 Antibody Rabbit Polyclonal ELISA 50129-RP01
    Anti-CD204 Antibody (PE) Rabbit Monoclonal FCM 50129-R004-P
    Anti-CD204 Antibody Mouse Monoclonal ELISA 10427-MM02
    Anti-CD204 Antibody Mouse Monoclonal ELISA(Cap) 10427-MM03
    Anti-CD204 Antibody Rabbit Polyclonal ELISA 10427-RP01
    Anti-CD204 Antibody Rabbit Polyclonal WB,ELISA 10427-T48
    Anti-CD204 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 10427-R005
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