Anti-CD204 Antibody (PE)

Cat: 50129-R004-P
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Anti-CD204 Antibody (PE) (Rabbit Monoclonal antibody) General Information
Product name
Anti-CD204 Antibody (PE)
Validated applications
FCM
Species reactivity
Reacts with: Mouse
Specificity
Mouse CD204
Immunogen
Recombinant Mouse MSR1 / CD204 protein (Catalog#50129-M07H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse MSR1 / CD204 (rM MSR1 / CD204; Catalog#50129-M07H; AAH03814.1; Trp 83-Val 354) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Source
Monoclonal Rabbit IgG Clone #004
Purification
Protein A
Formulation
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Conjugate
PE
Concentration
5 μl/Test, 0.1 mg/ml
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Anti-CD204 Antibody (PE) (Rabbit Monoclonal antibody) Validated Applications

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CD204 Antibody (PE) (Rabbit Monoclonal antibody) Images
Mouse MSR1/CD204 Flow Cytometry (FC) 2567
Profile of anti-MSR1 (CD204) reactivity on Raw264.7 cells analyzed by flow cytometry. Cells should be Fc-blocked by treatment with Mouse BD Fc Block™ purified anti-CD16/CD32 mAb 2.4G2 (Cat. No. 553141) prior to staining, washed, then stained with PE Rabbit anti-MSR1 (CD204).
Anti-CD204 Antibody (PE) Alternative Names
Anti-MRS-A Antibody;Anti-MSR Antibody;Anti-MSR-A Antibody;Anti-Scara1 Antibody;Anti-Scvr Antibody;Anti-SR-AI Antibody;Anti-SR-AII Antibody
CD204 Background Information

Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD204, MSR1 and SCARA1, is a single-pass type I I membrane protein which contains one collagen-like domain and one SRCR domain. Macrophages are distributed in all peripheral tissues and play a critical role in the first line of the innate immune defenses against bacterial infection by phagocytosis of bacterial pathogens through the macrophage scavenger receptor 1 (MSR1). MSR1 / SCARA1 is one of the membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). MSR1 / SCARA1 is also involved in chronic inflammation which is a risk factor for prostate cancer. MSR1 1 gene was identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer.

Full Name
macrophage scavenger receptor 1
References
  • Wang L. et al., 2003, Nat Genet. 35 (2): 128-9.
  • Chen Y.C. et al., 2008, Cancer Epidemiol Biomarkers Prev. 17 (4): 1001-3.
  • Shirato K. et al., 2009, Pflugers Arch. 459 (1): 93-103.
  • Sun J. et al., 2006, Prostate. 66 (7): 728-37.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CD204 Antibody Rabbit Monoclonal IHC-P,FCM,ICC/IF,IF 50129-R004
    Anti-CD204 Antibody (FITC) Rabbit Monoclonal FCM 50129-R004-F
    Anti-CD204 Antibody Rabbit Polyclonal ELISA,IHC-P 50129-RP02
    Anti-CD204 Antibody Rabbit Polyclonal ELISA 50129-RP01
    Anti-CD204 Antibody Mouse Monoclonal ELISA 10427-MM02
    Anti-CD204 Antibody Mouse Monoclonal ELISA(Cap) 10427-MM03
    Anti-CD204 Antibody Rabbit Polyclonal ELISA 10427-RP01
    Anti-CD204 Antibody Rabbit Polyclonal WB,ELISA 10427-T48
    Anti-CD204 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 10427-R005
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