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MSR1 / CD204 Antibody (FITC), Rabbit MAb
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MSR1 / CD204 Antibody (FITC), Rabbit MAb PDF Download

Catalog   Size (Price) Quantity In Stock Operation
50129-R004-F  
YES   
 

Primary antibody | Secondary antibody | Tag antibody | Isotype control antibody | Loading control antibody | Antibody Purification

MSR1 / CD204 Antibody Datasheet

  Order or Inquire for MSR1 / CD204 Antibody product Quality antibodies Antibody production services
 

MSR1 / CD204 Antibody Product Information

Immunogen :

Recombinant Mouse MSR1 / CD204 protein (Catalog#50129-M07H)

Reagents : FITC-conjugated rabbit monoclonal antibody

Clone ID :

004

Ig Type :

Rabbit IgG

Concentration :

10 μl/Test, 0.1 mg/ml

Formulation : Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Preparation :

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse MSR1 / CD204 (rM MSR1 / CD204; Catalog#50129-M07H; AAH03814.1; Trp 83-Val 354) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.

MSR1 / CD204 Antibody Usage Guide

Specificity :

Mouse MSR1 / CD204

  Has cross-reactivity in ELISA with

Rat MSR1

Flow Cytometry :
MSR1 / CD204 Flow Cytometry

Profile of anti-MSR1 (CD204) reactivity on Raw264.7 cells analyzed by flow cytometry. Cells should be Fc-blocked by treatment with Mouse BD Fc Block™ purified anti-CD16/CD32 mAb 2.4G2 (Cat. No. 553141) prior to staining, washed, then stained with FITC Rabbit anti-MSR1 (CD204).

Flow cytometry was performed on a BD FACSCalibur flow cytometry system

Please refer to www.sinobiological.com/Flow-Cytometry-FACS-Protocols-a-750.html for technical protocols.

Storage : This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

MSR1 / CD204 Antibody Related Products & Topics

MSR1 / CD204 Antibody Related Areas:

Immunology>>Innate Immunity>>Monocyte/Macrophage>>Scavenger Receptor>>MSR1/CD204

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Macrophage Markers>>MSR1/CD204

Proteins:

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
MSR1/CD204/SCARA1 Human MSR1/CD204 Protein, Recombinant 10427-H07H
MSR1/CD204/SCARA1 Mouse MSR1/CD204 Protein, Recombinant 50129-M07H
MSR1/CD204/SCARA1 Rat MSR1 / SCARA1 Protein, Recombinant 80363-R01H

Antibodies:

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
MSR1/CD204/SCARA1
WB, ELISA MSR1/CD204 Antibody, Mouse MAb 10427-MM02
Human
MSR1/CD204/SCARA1
WB, ELISA MSR1/CD204 Antibody, Rabbit MAb 10427-R005
Mouse
MSR1/CD204/SCARA1
WB, ELISA MSR1 / CD204 Antibody 50129-RP01
Mouse
MSR1/CD204/SCARA1
WB, ELISA MSR1 / CD204 Antibody (Antigen Affinity Purified) 50129-RP02
Human
MSR1/CD204/SCARA1
FCM MSR1 / CD204 Antibody ( FITC ) 50129-R004-F

MSR1 / CD204 Antibody Background

Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD204, MSR1 and SCARA1, is a single-pass type II membrane protein which contains onecollagen-like domain and oneSRCR domain. Macrophages are distributed in all peripheral tissues and play a critical role in the first line of the innate immune defenses against bacterial infection by phagocytosis of bacterial pathogens through the macrophage scavenger receptor 1 (MSR1). MSR1 / SCARA1 is one of the membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). MSR1 / SCARA1 is also involved in chronic inflammation which is a risk factor for prostate cancer. MSR1 1 gene was identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer.

References

  1. Wang,L.et al., 2003, Nat Genet. 35 (2): 128-9.
  2. Chen,Y.C. et al., 2008, Cancer Epidemiol Biomarkers Prev17 (4): 1001-3.
  3. Shirato,K. et al., 2009,Pflugers Arch459 (1): 93-103.
  4. Sun,J.et al., 2006, Prostate. 66 (7): 728-37.
 

 

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