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Human MSLN / Mesothelin Protein (His Tag)
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Human MSLN / Mesothelin Protein (His Tag) PDF Download

Catalog   Size (Price) Quantity In Stock Operation
13128-H08H  
YES   
 

Protein Production & Purification Service | Recombinant Cytokines & Growth Factors

Mesothelin Protein Datasheet

 

MSLN / Mesothelin Protein Price Inquiry ( Available Sizes )

MSLN / Mesothelin Protein Product Information

Synonym : MSLN
Protein Construction:

A DNA sequence encoding the human MSLN (Q13421-2) (Met1-Arg286) was expressed with a polyhistidine tag at the C-terminus.

Source: Human
Expression Host: Human Cells

MSLN / Mesothelin Protein QC Testing

Purity: > 90% as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE

MSLN / Mesothelin protein

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Leu 37
Molecular Mass:

The recombinant human MSLN consists of  261 amino acids and predicts a molecular mass of 28.2 KDa. It migrates as an approximately 33 KDa band in SDS-PAGE under reducing conditions.

Formulation: Lyophilized from sterile PBS, pH 7.4.
  1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
  2. Please contact us for any concerns or special requirements.

MSLN / Mesothelin Protein Usage Guide

Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

MSLN / Mesothelin Protein Related Products & Topics

Related Areas:

Proteins:

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat No
MSLN / Mesothelin Human MSLN / Mesothelin (aa 296-580) Protein, Recombinant 13128-H01H
MSLN / Mesothelin Human MSLN / Mesothelin Protein, Recombinant 13128-H02H
MSLN / Mesothelin Human MSLN / Mesothelin Protein, Recombinant 13128-H08H

Antibodies:

MSLN / Mesothelin Protein Description

Megakaryocyte potentiating factor is a member of the mesothelin family. This family consists of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Both megakaryocyte potentiating factor and the cleaved form of mesothelin are N-glycosylated. Mesothelin is a tumour differentiation antigen that is normally present on the mesothelial cells lining the pleura, peritoneum and pericardium. Megakaryocyte potentiating factor is secreted by several mesothelioma cell lines and is frequently elevated in the blood of patients with mesothelioma. Measurement of this protein may be useful in following the response of mesothelioma to treatment. Megakaryocyte potentiating factor interacts with MUC16 and potentiates megakaryocyte colony formation in vitro. Its membrane-anchored forms may play a role in cellular adhesion.

References

  1. Chang MC. et al., 2012, Biochem J. 442 (2): 293-302.
  2. Nelson HH. et al., 2011, Epigenetics. 6 (8): 1029-34.
  3. Bournet B. et al., 2012, Pancreatology. 12 (1): 27-34.
 
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"