Anti-MOG Antibody

Cat: 10364-RP01
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All MOG Reagents
Anti-MOG Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-MOG Antibody
Validated applications
Species reactivity
Reacts with: Human
Human MOG
Recombinant Human MOG protein (Catalog#10364-H08E)
Produced in rabbits immunized with purified, recombinant Human MOG (rh MOG; Catalog#10364-H08E; NP_996532.2; Gly 30-Tyr 149). Total IgG was purified by Protein A affinity chromatography .
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-MOG Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-MOG Antibody Alternative Names
Anti-BTN6 Antibody;Anti-BTNL11 Antibody;Anti-MOGIG2 Antibody;Anti-NRCLP7 Antibody
MOG Background Information

Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to immunoglobulin superfamily, and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only in the CNS with very low content (approximately 0.1% total proteins) in oligodendrogliocyte membrane. Three possible functions for MOG were suggested: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions between myelin and the immune system, in particular, the complement cascade. A direct interaction might exist between the membrane-associated regions of MOG and the myelin-specific glycolipid galactocerebroside (Gal-C), and such an interaction may have important consequences regarding the membrane topology and function of both molecules. It is considered that MOG is an autoantigen capable to produce a demyelinating multiple sclerosis-like disease in experimental animals.

Full Name
myelin oligodendrocyte glycoprotein
  • Chekhonin VP, et al. (2003) Myelin oligodendrogliocyte glycoprotein: the structure, functions, role in pathogenesis of demyelinating disorders. Biomed Khim. 49(5): 411-23.
  • Hilton AA, et al. (1995) Characterization of cDNA and Genomic Clones Encoding Human Myelin Oligodendrocyte Glycoprotein. J Neurochem. 65(1): 309-18.
  • Johns TG, et al. (1999) The Structure and Function of Myelin Oligodendrocyte Glycoprotein. J Neurochem. 72(1): 1-9.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-MOG Antibody Mouse Monoclonal IHC-P 80425-MM04T
    Anti-MOG Antibody Rabbit Polyclonal WB,ELISA,IHC-P 80425-T56
    Anti-MOG Antibody Rabbit Polyclonal ELISA,IHC-P 51046-T24
    Anti-MOG Antibody Rabbit Polyclonal ELISA,IHC-P 10364-RP02
    Anti-MOG Antibody Mouse Monoclonal ELISA 10364-MM05
    Anti-MOG Antibody Rabbit Monoclonal ELISA 10364-R013
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