Anti-MMP-9 Antibody

Cat: 10327-RM05

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All MMP-9 Reagents
Anti-MMP-9 Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-MMP-9 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human MMP-9
Recombinant Human MMP9 protein (Catalog#10327-H08H)
This antibody was obtained from a rabbit immunized with purified, recombinant Human matrix metallopeptidase 9 (rh MMP9; Catalog#10327-H08H; Met 1-Asp 707; NP_004985.2).
Monoclonal Rabbit IgG Clone #31
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-MMP-9 Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-MMP-9 Antibody Alternative Names
Anti-CLG4B Antibody;Anti-GELB Antibody;Anti-MANDP2 Antibody;Anti-MMP-9 Antibody
MMP-9 Background Information

Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogenesis, differentiation, angiogenesis and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases and tumor invasion. MMP9, also known as 92-kDa gelatinase B/type IV collagenase, is secreted from neutrophils, macrophages, and a number of transformed cells, and is the most complex family member in terms of domain structure and regulation of its activity. It plays an important role in tissue remodelling in normal and pathological inflammatory processes. MMP-9 is a major secretion product of macrophages and a component of cytoplasmic granules of neutrophils, and is particularly important in the pathogenesis of inflammatory, infectious, and neoplastic diseases in many organs including the lung. This enzyme is also secreted by lymphocytes and stromal cells upon stimulation by inflammatory cytokines, or upon delivery of bi-directional activation signals following integrin-mediated cell-cell or cell-extracellular matrix (ECM) contacts. Since the integrity of the tissue architecture is closely dependent of the delicate balance between MMPs and their inhibitors, excessive production of MMP-9 is linked to tissue damage and degenerative inflammatory disorders. As a consequence, regulation of gene transcription and tissue-specific expression of MMP-9 in normal and diseased states are being actively investigated to pave the way for new therapeutic targets. In addition, the dramatic overexpression of MMP-9 in cancer and various inflammatory conditions clearly points to the molecular mechanisms controlling its expression as a potential target for eventual rational therapeutic intervention.

Full Name
matrix metallopeptidase 9
  • St-Pierre Y, et al. (2003) Emerging features in the regulation of MMP-9 gene expression for the development of novel molecular targets and therapeutic strategies. Curr Drug Targets Inflamm Allergy. 2(3): 206-15.
  • St-Pierre Y, et al. (2004) Regulation of MMP-9 gene expression for the development of novel molecular targets against cancer and inflammatory diseases. Expert Opin Ther Targets. 8(5): 473-89.
  • Chakrabarti S, et al. (2005) Matrix metalloproteinase-2 (MMP-2) and MMP-9 in pulmonary pathology. Exp Lung Res. 31(6): 599-621.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-MMP-9 Antibody Rabbit Monoclonal ELISA 80049-R213
    Anti-MMP-9 Antibody Rabbit Polyclonal ELISA,IHC-P 80049-T24
    Anti-MMP-9 Antibody Rabbit Polyclonal ELISA 80049-RP02
    Anti-MMP-9 Antibody Rabbit Polyclonal ELISA 80049-RP01
    Anti-MMP-9 Antibody Mouse Monoclonal ELISA(Cap) 80049-MM01
    Anti-MMP-9 Antibody Mouse Monoclonal ELISA 80049-MM04
    Anti-MMP-9 Antibody Rabbit Polyclonal ELISA 50560-T16
    Anti-MMP-9 Antibody Rabbit Monoclonal WB 50560-R002
    Anti-MMP-9 Antibody Rabbit Polyclonal ELISA 50560-RP01
    Anti-MMP-9 Antibody Rabbit Polyclonal IHC-P 10327-T08
    Anti-MMP-9 Antibody Rabbit Monoclonal ELISA 10327-RM04
    Anti-MMP-9 Antibody Rabbit Polyclonal ELISA 10327-RP06
    Anti-MMP-9 Antibody Mouse Monoclonal ELISA,ELISA(Cap) 10327-MM06
    Anti-MMP-9 Antibody (Biotin) Rabbit Monoclonal ELISA 10327-R043-B
    Anti-MMP-9 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 10327-R043
    Anti-MMP-9 Antibody Mouse Monoclonal ELISA 10327-MM01
    Anti-MMP-9 Antibody Rabbit Polyclonal ELISA,IHC-P 10327-T24
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