Anti-MMP-8 Antibody (FITC)

Cat: 10254-R023-F
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Anti-MMP-8 Antibody (FITC) (Rabbit Monoclonal antibody) General Information
Product name
Anti-MMP-8 Antibody (FITC)
Validated applications
FCM
Species reactivity
Reacts with: Human
Specificity
Human MMP-8
Immunogen
Recombinant Human MMP-8 protein (Catalog#10254-H08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human MMP-8 (rh MMP-8; Catalog#10254-H08H; NP_002415.1; Met 1-Gly 467) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Source
Monoclonal Rabbit IgG Clone #023
Purification
Protein A
Formulation
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Conjugate
FITC
Concentration
10 μl/Test, 0.1 mg/ml
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Anti-MMP-8 Antibody (FITC) (Rabbit Monoclonal antibody) Validated Applications

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-MMP-8 Antibody (FITC) (Rabbit Monoclonal antibody) Images
Human MMP-8 / MMP8 Flow Cytometry (FC) 5085
Flow cytometric analysis of Human MMP8 expression in Jurkat cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and then stained with PE Rabbit anti-MMP8(10254-R023-P). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Anti-MMP-8 Antibody (FITC) Alternative Names
Anti-CLG1 Antibody;Anti-HNC Antibody;Anti-MMP-8 Antibody;Anti-PMNL-CL Antibody
MMP-8 Background Information

Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases and tumor invasion. Neutrophil collagenase, also known as Matrix metalloproteinase-8, MMP-8, and CLG1, is a member of the peptidase M10A family. MMP-8 may affect the metastatic behaviour of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 in the tumour may have a protective effect against lymph node metastasis. MMP-8 may affect the metastatic behaviour of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 participates in wound repair by contributing to the resolution of inflammation and open the possibility to develop new strategies for treating wound healing defects.

Full Name
matrix metallopeptidase 8
References
  • Hasty K.A., et al.,(1990), Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases. J. Biol. Chem. 265:11421-11424.
  • Blaeser J., et al., (1991), Mercurial activation of human polymorphonuclear leucocyte procollagenase.Eur. J. Biochem. 202:1223-1230.
  • Blaeser J., et al.,(1991), Mercurial activation of human polymorphonuclear leucocyte procollagenase. Eur. J. Biochem. 202:1223-1230.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-MMP-8 Antibody Rabbit Polyclonal ELISA 50493-RP01
    Anti-MMP-8 Antibody Rabbit Polyclonal ELISA 50493-T16
    Anti-MMP-8 Antibody Rabbit Polyclonal WB,ELISA 10254-RP02
    Anti-MMP-8 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 10254-R102
    Anti-MMP-8 Antibody Rabbit Monoclonal ELISA(Cap) 10254-R206
    Anti-MMP-8 Antibody Rabbit Polyclonal WB,ELISA 10254-RP01
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