Anti-MICB Antibody

Cat: 10759-RP02
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All MICB Reagents
Anti-MICB Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-MICB Antibody
Validated applications
Species reactivity
Reacts with: Human
Human MICB
Recombinant Human MICB protein (Catalog#10759-H08H)
Produced in rabbits immunized with purified, recombinant Human MICB (rh MICB; Catalog#10759-H08H; NP_005922.2; Met 1-Gly 298). MICB specific IgG was purified by Human MICB affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-MICB Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  
IHC-P 1:500-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-MICB Antibody (Rabbit Polyclonal antibody) Images
Human MICB  Immunohistochemistry(IHC) 3894
Immunochemical staining of human MICB in human breast carcinoma with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Anti-MICB Antibody Alternative Names
Anti-PERB11.2 Antibody
MICB Background Information

MHC class I polypeptide-related sequence B, also known as MICB, is a heavily glycosylated protein serving as a ligand for the type I I receptor NKG2D. MICB shares 85% amino acid identity with MICA, a closely related protein, both of which contain three extracellular immunoglobulin-like domains, but without capacity to bind peptide or interact with beta-2-microglobulin. acting as a stress-induced self-antigen, binding of MICB to the NKG2D receptor activates the cytolytic response of natural killer (NK) cells, CD8+αβ T cells, and γδ T cells on which the receptor is expressed. MICA/B are minimally expressed on normal cells, but are frequently expressed on epithelial tumors and can be induced by bacterial and viral infections. MICA/B recognition thus is involved in tumor surveillance, viral infections, and autoimmune diseases.

Full Name
MHC class I polypeptide-related sequence B
  • Bauer, S. et al., 1999, Science. 285:727-729.
  • Braud, V.M. et al., 1999, Curr. Opin. Immunol. 11: 100-108.
  • Groh, V. et al., 2001, Nature Immunol. 2: 255-260.
  • Stephens, H., 2001, Trends Immunol. 22: 378-385.
  • Borrego, F. et al., 2002, Mol. Immunol. 38: 637–660.
  • Groh, V. et al., 2002, Nature. 419:734-738.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-MICB Antibody Rabbit Polyclonal WB,ELISA 10759-T48
    Anti-MICB Antibody (APC) Mouse Monoclonal FCM 10759-MM12-A
    Anti-MICB Antibody Rabbit Monoclonal WB 10759-R102
    Anti-MICB Antibody Rabbit Polyclonal ELISA 10759-RP01
    Anti-MICB Antibody Rabbit Polyclonal WB,IHC-P 10759-T40
    Anti-MICB Antibody Mouse Monoclonal ELISA(Cap) 10759-MM04
    Anti-MICB Antibody Mouse Monoclonal ELISA,FCM 10759-MM12
    Anti-MICB Antibody (FITC) Mouse Monoclonal FCM 10759-MM12-F
    Anti-MICB Antibody (PE) Mouse Monoclonal FCM 10759-MM12-P
    Anti-MICB Antibody Rabbit Monoclonal ELISA 10759-R103
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