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> Antibody > Rabbit PAb Antibody > MESDC2 / MESD Antibody (Antigen Affinity Purified) MESDC2 / MESD Antibody (Antigen Affinity Purified) 
| Catalog | Size (Price) | Quantity | In Stock | Operation | Other Information |
| 10949-RP02 |
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LDLR Chaperone MESD Antibody ( Antigen Affinity Purified )
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Order or Inquire for MESDC2 Antibody product |  |
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Detection limit is 0.5 ng/lane in WB | ||
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Detection limit is 0.0049 ng/well in ELISA |
MESDC2 / MESD Antibody Product Information
| Immunogen : |
Recombinant human MESD protein ( Catalog#10949-H08H ) |
| Antibody Type : | Rabbit Polyclonal Antibody ( Antibody Purification Platform ) |
| Ig Type : |
Rabbit IgG |
| Formulation : | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation : |
Produced in rabbits immunized with purified, human cell-derived, recombinant human MESDC2 ( rh MESDC2 ; Catalog#10949-H08H ; NP_055969.1 ; Ala 34 - Lys 230 ). MESDC2 specific IgG was purified by human MESDC2 affinity chromatography |
MESDC2 / MESD Antibody Usage Guide
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Specificity : |
Human MESDC2 / MESD |
| Western blot : | This antibody can be used at 0.1 - 0.2 μg/mL with the appropriate secondary reagents to detect human MESDC2 in WB. Using a DAB detection system, the detection limit for human MESDC2 is approximately 0.5 ng/lane under non-reducing conditions and reducing conditions |
| Direct ELISA ： | This antibody can be used at 0.1 - 0.2 μg/mL with the appropriate secondary reagents to detect human MESDC2. The detection limit for human MESDC2 is approximately 0.0049 ng/well |
| Storage : | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
MESDC2 / MESD Antibody Related Products & Topics
Related Areas:
Stem Cell>>Embryonic Stem Cell (ESC)>>Embryonic Cell Lineage Marker>>MESDC2
Proteins:
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| MESDC2< | Human | MESDC2 Protein, Recombinant | 10949-H08H |
Antibodies:
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human MESDC2 |
WB, ELISA | MESDC2 Antibody, Rabbit PAb | 10949-RP01 |
| Human MESDC2 |
WB, ELISA | MESDC2 Antibody, Rabbit PAb (Antigen Affinity Purified) | 10949-RP02 |
MESDC2 / MESD Antibody Background
LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61 and MESDC2, is a member of the MESD family. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity resides in the N- and C-terminal unstructured regions. MESDC2 acts as a modulator of the Wnt pathway, since some LDLRs are coreceptors for the canonical Wnt pathway. MESDC2 is essential for specification of embryonic polarity and mesoderm induction.
References
- Scanlan M.J. et al., 1999, Int. J. Cancer 83:456-464.
- Veltman,IM. et al.,2005, Hum Mol Genet 14 (14):1955-63.
- Koduri V. et al., 2007, Biochemistry 46:6570-7.
