All MCP3 reagents are produced in house and quality controlled, including 5 MCP3 Antibody, 15 MCP3 Gene, 3 MCP3 Protein, 2 MCP3 qPCR. All MCP3 reagents are ready to use.
Recombinant MCP3 proteins are expressed by E. coli with fusion tags as N-His, C-His.
MCP3antibodies are validated with different applications, which are ELISA, FCM, ICC/IF, IF, WB.
MCP3cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each MCP3 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 7(CCL7), also known as MCP-3, is a isform of the C-C chemokine subfamily of the chemokine family which is produced by certain tumor cells and by macrophages. It also own two adjacent N-terminal cysteine residues. Chemokine ligand 7(CCL7) spacifically attracts monocytes, and regulates macrophage function.