MBL1 (Protein|Antibody|cDNA Clone|ELISA Kit)

All MBL1 reagents are produced in house and quality controlled, including 26 MBL1 Gene, 2 MBL1 Lysate, 2 MBL1 Protein, 2 MBL1 qPCR. All MBL1 reagents are ready to use.

Recombinant MBL1 proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, N-His.

MBL1 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each MBL1 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

MBL1 Protein (2)

Species

MBL1 Protein, Rat, Recombinant (Fc Tag)

80251-R02H

Expression host: HEK293 Cells

Rat MBL-1 Protein 12503

MBL1 Protein, Mouse, Recombinant (His Tag)

50069-M07H

Expression host: HEK293 Cells

Mouse MBL-1 Protein 11363
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MBL1 cDNA Clone (26)

Mouse
Rat

MBL1 qPCR Primer (2)

MBL1 Lysate (2)

Mannose-binding lectin (MBL), also named mannose or mannan-binding protein (MBP), is a C-type lectin which participates in the innate immune system as an activator of the complement system and as opsonin after binding to certain carbohydrate structures on microorganisms and pathogens. Its function appears to be pattern recognition in the first line of defense in the pre-immune host. MBL recognizes carbohydrate patterns found on the surface of a large number of pathogenic micro-organisms including bacteria, viruses, protozoa and fungi. Binding of MBL to a micro-organism results in activation of the lectin pathway of the complement system. Two forms of MBL, MBL-A and MBL-C, were characterized in rodents, rabbits, bovine and rhesus monkeys, whereas only one form was identified in humans, chimpanzees and chickens. The two forms are encoded by two distinct genes named MBL1 and MBL2, which have been identified in many species including the pig. The MBL1 and MBL2 genes encode mannan-binding lectins (MBL) A and C, respectively, that are collagenous lectins (collectins) produced mainly by the liver. The MBL1 gene encodes MBL-A, which has bacteria-binding properties in pigs and rodents but is mutated to a pseudogene in humans and chimpanzees. Deficiency of MBL is probably the most common human immunodeficiency and is associated with an increased risk of mucosally acquired infections including meningococcal disease. MBL could modify disease susceptibility by modulating macrophage interactions with mucosal organisms at the site of initial acquisition.
Protein
Gene
qPCR
Lysate
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