Anti-DPEP2 Antibody

Cat: 13806-RP01
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Anti-DPEP2 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-DPEP2 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human DPEP2
Immunogen
Recombinant Human MBD2 / DPEP2 protein (Catalog#13806-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human MBD2 / DPEP2 (rh MBD2 / DPEP2; Catalog#13806-H08H; AAH24021.1; Met1-Ser376). Total IgG was purified by Protein A affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-DPEP2 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-DPEP2 Antibody Alternative Names
Anti-MBD2 Antibody
DPEP2 Background Information

DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1),membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3).MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen.MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes.

Full Name
dipeptidase 2
References
  • Geetha M. Habib.et al.,2003,The FASEB Journal.8
  • Habib,G.M.,and Lieberman,M.W.1999,Adv.Exp.Med.Biol.469,295-300
  • Campbell, B. Jet al.,1984,J.Biol.Chem.259,14586-14590.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-DPEP2 Antibody Rabbit Polyclonal ELISA 13806-T16
    info info
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