Anti-MAX Antibody

Cat: 12885-RP01
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Anti-MAX Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-MAX Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human MAX
Immunogen
Recombinant Human MAX / MYC associated factor X protein (Catalog#12885-H20B)
Preparation
Produced in rabbits immunized with purified, recombinant Human MAX / MYC associated factor X (rh MAX / MYC associated factor X; Catalog#12885-H20B; NP_002373; Met1-Ser160). Total IgG was purified by Protein A affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-MAX Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-MAX Antibody Alternative Names
Anti-bHLHd4 Antibody
MAX Background Information

MYC associated factor X contains 1 basic helix-loop-helix (bHLH) domain and belongs to MAX family. It is highly expressed in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle. MYC associated factor X can form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. MYC associated factor X may also repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Multiple alternatively spliced transcript variants have been described for MYC associated factor X gene but the full-length nature for some of them is unknown.

Full Name
MYC associated factor X
References
  • Mac Partlin M, et al. (2003) Interactions of the DNA mismatch repair proteins MLH1 and MSH2 with c-MYC and MAX. Oncogene. 22(6):819-25.
  • Cheng SW, et al. (1999) c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function. Nat enet. 22(1):102-5.
  • McMahon SB, et al. (1998) The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. Cell. 94(3):363-74.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-MAX Antibody Rabbit Polyclonal WB,ELISA,IP 12885-T52
    Anti-MAX Antibody Rabbit Polyclonal WB 100962-T32
    Anti-MAX Antibody Mouse Monoclonal WB,ELISA 12885-MM01
    Anti-MAX Antibody Rabbit Monoclonal WB,ELISA,FCM,ICC/IF,IF,IP 12885-R103
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