All Tau reagents are produced in house and quality controlled, including 2 Tau Antibody, 29 Tau Gene, 1 Tau Protein, 1 Tau qPCR. All Tau reagents are ready to use.
Recombinant Tau proteins are expressed by E. coli with fusion tags as N-His.
Tauantibodies are validated with different applications, which are ELISA.
TaucDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Tau of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP). In humans, these proteins are mostly found in neurons compared to non-neuronal cells. One of tau's main functions is to modulate the stability of axonal microtubules. Other nervous system MAPs may perform similar functions, as suggested by tau knockout mice, who did not show abnormalities in brain development - possibly because of compensation in tau deficiency by other MAPs.