Anti-M-CSF Antibody

Cat: 51112-RP01
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All M-CSF Reagents
Anti-M-CSF Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-M-CSF Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse M-CSF
Recombinant Mouse M-CSF / CSF-1 protein (Catalog#51112-M08H)
Produced in rabbits immunized with purified, recombinant Mouse M-CSF / CSF-1 (rM M-CSF / CSF-1; Catalog#51112-M08H; P07141-1; Met1-Glu262). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-M-CSF Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-M-CSF Antibody Alternative Names
Anti-C87615 Antibody;Anti-Csfm Antibody;Anti-MCSF Antibody;Anti-op Antibody
M-CSF Background Information

Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. M-CSF/CSF-1 is known to facilitate monocyte survival, monocyte-to-macrophage conversion, and macrophage proliferation. M-CSF/CSF-1 is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. It binds to the Colony stimulating factor 1 receptor. M-CSF/CSF-1 may also be involved in development of the placenta. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage, but also by regulating endothelial cell chemokine expression.

Full Name
colony stimulating factor 1 (macrophage)
  1. Pandit J. et al., 1992, Science. 258: 1358-62.
  2. Tokai M. et al., 2000, J Bacteriol. 182 (10): 2865-8.
  3. Fan X. et al., 2001, Am J Physiol Endocrinol Metab. 280 (1): E103-11.
  4. Frangogiannis NG. et al., 2003, Am J Physiol Heart Circ Physiol. 285 (2): H483-92.
  5. Cupp JS. et al., 2007, Am J Surg Pathol. 31 (6): 970-6.
Product Description Host Clonality Application Catalog# (PDF)
Anti-M-CSF Antibody Rabbit Monoclonal ELISA 51112-R133
Anti-M-CSF Antibody Rabbit Polyclonal ELISA 51112-T16
Anti-M-CSF Antibody Rabbit Monoclonal ELISA,ELISA(Cap) 51112-R003
Anti-M-CSF Antibody Rabbit Monoclonal ELISA 51112-R007
Anti-M-CSF Antibody Mouse Monoclonal ELISA 11792-MM16
Anti-M-CSF Antibody Mouse Monoclonal FCM 11792-MM03
Anti-M-CSF Antibody Rabbit Monoclonal ELISA(Cap) 11792-R028
Anti-M-CSF Antibody Rabbit Monoclonal ELISA(Det) 11792-R101
Anti-M-CSF Antibody Rabbit Polyclonal ELISA 11792-RP01
Anti-M-CSF Antibody Rabbit Polyclonal ELISA 11792-RP02
Anti-M-CSF Antibody Rabbit Monoclonal ELISA 11792-R033
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