All SLAMF6 reagents are produced in house and quality controlled, including 17 SLAMF6 Antibody, 2 SLAMF6 ELISA, 13 SLAMF6 Gene, 4 SLAMF6 Lysate, 4 SLAMF6 Protein, 2 SLAMF6 qPCR. All SLAMF6 reagents are ready to use.
Recombinant SLAMF6 proteins are expressed by HEK293 Cells with fusion tags as C-His, C-human IgG1-Fc, C-cleavage.
SLAMF6antibodies are validated with different applications, which are ELISA, IHC-P, FCM, ELISA(Cap), ELISA(Det), WB.
SLAMF6cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each SLAMF6 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
SLAMF6ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly108, is a single-pass type I membrane protein which belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly108 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly108 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly108 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly108 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly108 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.