Anti-SLAMF6 Antibody

Cat: 50275-RP01

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Anti-SLAMF6 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-SLAMF6 Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse SLAMF6
Recombinant Mouse Ly108 / SLAMF6 protein (Catalog#50275-M08H)
Produced in rabbits immunized with purified, recombinant Mouse Ly108 / SLAMF6 (rM Ly108 / SLAMF6; Catalog#50275-M08H; NP_109635.1; Met 1-Asn 239). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-SLAMF6 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-SLAMF6 Antibody Alternative Names
Anti-KAL1 Antibody;Anti-KAL1b Antibody;Anti-Ly108 Antibody;Anti-NTB-A Antibody;Anti-NTBA Antibody;Anti-SF2000 Antibody
SLAMF6 Background Information

SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly108, is a single-pass type I membrane protein which belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly108 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly108 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly108 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly108 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly108 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.

Full Name
SLAM family member 6
  • Gray CW. et al., 2000, Eur J Biochem. 267 (18): 5699-710.
  • Bottino C. et al., 2001, J Exp Med. 194 (3): 235-46.
  • Valdez PA. et al., 2004, J Biol Chem. 279 (18): 18662-9.
  • Claus M. et al., 2007, Front Biosci. 13: 956-65.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-SLAMF6 Antibody Rabbit Polyclonal ELISA 50275-RP02
    Anti-SLAMF6 Antibody Rabbit Monoclonal WB 50275-R040
    Anti-SLAMF6 Antibody Rabbit Polyclonal ELISA 11945-RP01
    Anti-SLAMF6 Antibody Mouse Monoclonal ELISA(Cap) 11945-MM10
    Anti-SLAMF6 Antibody Rabbit Monoclonal IHC-P 11945-R005
    Anti-SLAMF6 Antibody Rabbit Monoclonal FCM 11945-R105
    Anti-SLAMF6 Antibody Rabbit Polyclonal ELISA 11945-RP02
    Anti-SLAMF6 Antibody Mouse Monoclonal ELISA 11945-MM08
    Anti-SLAMF6 Antibody (FITC) Rabbit Monoclonal FCM 11945-R105-F
    Anti-SLAMF6 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 11945-R110
    Anti-SLAMF6 Antibody (FITC) Rabbit Monoclonal FCM 11945-R002-F
    Anti-SLAMF6 Antibody (APC) Rabbit Monoclonal FCM 11945-R002-A
    Anti-SLAMF6 Antibody Rabbit Monoclonal FCM 11945-R002
    Anti-SLAMF6 Antibody (APC) Rabbit Monoclonal FCM 11945-R105-A
    Anti-SLAMF6 Antibody (PE) Rabbit Monoclonal FCM 11945-R105-P
    Anti-SLAMF6 Antibody (PE) Rabbit Monoclonal FCM 11945-R002-P
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