Anti-SLAMF6 Antibody

Cat: 11945-RP02
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All SLAMF6 Reagents
CRO Services
Product recommended

All SLAMF6 Reagents
Anti-SLAMF6 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-SLAMF6 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human SLAMF6
Immunogen
Recombinant Human Ly108 / SLAMF6 protein (Catalog#11945-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human Ly108 / SLAMF6 (rh Ly108 / SLAMF6; Catalog#11945-H08H; Q96DU3-1; Met 1-Met 226). Ly108 / SLAMF6 specific IgG was purified by Human Ly108 / SLAMF6 affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-SLAMF6 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-SLAMF6 Antibody Alternative Names
Anti-CD352 Antibody;Anti-KALI Antibody;Anti-KALIb Antibody;Anti-Ly108 Antibody;Anti-NTB-A Antibody;Anti-NTBA Antibody;Anti-SF2000 Antibody
SLAMF6 Background Information

SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly108, is a single-pass type I membrane protein which belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly108 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly108 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly108 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly108 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly108 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.

Full Name
SLAM family member 6
References
  • Gray CW. et al., 2000, Eur J Biochem. 267 (18): 5699-710.
  • Bottino C. et al., 2001, J Exp Med. 194 (3): 235-46.
  • Valdez PA. et al., 2004, J Biol Chem. 279 (18): 18662-9.
  • Claus M. et al., 2007, Front Biosci. 13: 956-65.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-SLAMF6 Antibody Rabbit Monoclonal WB 50275-R040
    Anti-SLAMF6 Antibody Rabbit Polyclonal ELISA 50275-RP01
    Anti-SLAMF6 Antibody Rabbit Polyclonal ELISA 50275-RP02
    Anti-SLAMF6 Antibody (APC) Rabbit Monoclonal FCM 11945-R105-A
    Anti-SLAMF6 Antibody (FITC) Rabbit Monoclonal FCM 11945-R002-F
    Anti-SLAMF6 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 11945-R110
    Anti-SLAMF6 Antibody Rabbit Monoclonal IHC-P 11945-R005
    Anti-SLAMF6 Antibody (APC) Rabbit Monoclonal FCM 11945-R002-A
    Anti-SLAMF6 Antibody Mouse Monoclonal ELISA 11945-MM08
    Anti-SLAMF6 Antibody Rabbit Monoclonal FCM 11945-R105
    Anti-SLAMF6 Antibody (FITC) Rabbit Monoclonal FCM 11945-R105-F
    Anti-SLAMF6 Antibody (PE) Rabbit Monoclonal FCM 11945-R105-P
    Anti-SLAMF6 Antibody Mouse Monoclonal ELISA(Cap) 11945-MM10
    Anti-SLAMF6 Antibody Rabbit Polyclonal ELISA 11945-RP01
    Anti-SLAMF6 Antibody (PE) Rabbit Monoclonal FCM 11945-R002-P
    Anti-SLAMF6 Antibody Rabbit Monoclonal FCM 11945-R002
    info info
    添加购物车成功! 添加购物车失败!