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Latexin / LXN Antibody, Rabbit MAb
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Latexin / LXN Antibody, Rabbit MAb PDF Download

Catalog   Size (Price) Quantity In Stock Operation
50050-R040  

YES   
 

Primary antibody | Secondary antibody | Tag antibody | Isotype control antibody | Loading control antibody | Antibody Purification

Latexin / LXN Antibody Datasheet

  Order or Inquire for Latexin / LXN Antibody product Quality antibodies Antibody production services
  Detection limit is 0.039 ng/well in ELISA
 

Latexin / LXN Antibody Product Information

Immunogen :

Recombinant Mouse Latexin / LXN protein (Catalog#50050-M07E)

Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )

Clone ID :

040

Ig Type :

Rabbit IgG

Formulation : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
Preparation :

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Latexin / LXN (rM Latexin / LXN; Catalog#50050-M07E; NP_058033.2; Glu 2-Glu 222).

Latexin / LXN Antibody Usage Guide

Specificity :

Mouse Latexin / LXN

 

No cross-reactivity in ELISA with

Human LXN

Direct ELISA : This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse LXN. The detection limit for Mouse LXN is approximately 0.039 ng/well.
Storage : This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Latexin / LXN Antibody Related Products & Topics

Related Areas:

Enzyme>>Protease & Regulator>>Metalloprotease & Regulator>>Latexin/Lxn

Stem Cell>>Neural Stem Cell (NSC)>>Neuronal Cell Markers>>Latexin/Lxn

Immunology>>Innate Immunity>>Mast Cell>>Latexin/Lxn

Immunology>>Innate Immunity>>Monocyte/Macrophage>>Macrophage Marker>>Latexin/Lxn

Proteins:

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
Latexin/Lxn Human Latexin/Fc Protein, Recombinant 10211-H01H
Latexin/Lxn Human Latexin Protein, Recombinant 10211-H07E
Latexin/Lxn Mouse Latexin Protein, Recombinant 50050-M07E

Antibodies:

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
Latexin/Lxn
WB, ELISA Latexin/Lxn Antibody, Mouse MAb 10211-MM04
Human
Latexin/Lxn
WB, ELISA Latexin / LXN Antibody 10211-R101
Human
Latexin/Lxn
WB, ELISA Rabbit Polyclonal Antibody 10211-RP01
Human
Latexin/Lxn
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified) 10211-RP02
Mouse
Latexin/Lxn
WB, ELISA Latexin / LXN Antibody (Antigen Affinity Purified) 50050-RP02
Mouse
Latexin/Lxn
ELISA Latexin / LXN Antibody 50050-R009
Mouse
Latexin/Lxn
ELISA Latexin / LXN Antibody 50050-R040

Latexin / LXN Antibody Background

Latexin, also known as tissue or endogenous carboxypeptidase inhibitor (TCI or ECI), is the only known endogenous specific inhibitor of zinc-dependent metallocarboxypeptidases (MCPs) present in mammalians so far. Latexin is originally identified as a molecular marker for the regional specification of the neocortex in development in rats. The 222 amino acid latexin in human shows different expression distribution with high levels in heart, prostate, ovary, kidney, pancreas, and colon, but only moderate or low levels in other tissues including brain. Latexin is also expressed at high levels and is inducible in macrophages in concert with other protease inhibitors and potential protease targets, and thus is suggested to play a role in inflammation and innate immunity pathways. Despite of the non-detectable sequence similarity with plant and parasite inhibitors, Latexin is related to a human putative tumor suppressor protein, TIG1. In addition, Latexin is also implicated in Alzheimer's disease.

References

  1. Liu, Q. et al., 2000, Mol. Biol. Rep. 27: 241-246.
  2. Aagaard, A. et al., 2005, Structure 13: 309-317.
  3. Pallares, I. et al., 2005, Proc. Natl. Acad. Sci. USA. 102: 3978-3983.
 
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"