Anti-Lactoferrin Antibody

Cat: 11096-RP02
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Anti-Lactoferrin Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-Lactoferrin Antibody
Validated applications
ELISA,IHC-P
Species reactivity
Reacts with: Human
Specificity
Human Lactoferrin
Immunogen
Recombinant Human Lactotransferrin / LTF protein (Catalog#11096-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human Lactotransferrin / LTF (rh Lactotransferrin / LTF; Catalog#11096-H08H; P02788; Met 1-Lys 710). Lactotransferrin / LTF specific IgG was purified by Human Lactotransferrin / LTF affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Lactoferrin Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  
IHC-P 1:500-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Lactoferrin Antibody (Rabbit Polyclonal antibody) Images
Human Lactotransferrin/LTF Immunohistochemistry(IHC) 3922
Immunochemical staining of human LTF in human spleen with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Human Lactotransferrin/LTF Immunohistochemistry(IHC) 3923
Immunochemical staining of human LTF in human placenta with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). The image showing positive staining of leukocytes.
Anti-Lactoferrin Antibody Alternative Names
Anti-GIG12 Antibody;Anti-HEL110 Antibody;Anti-HLF2 Antibody;Anti-LF Antibody
Lactoferrin Background Information

Lactotransferrin, also known as Lactoferrin, Talalactoferrin and LTF, is a secreted protein which belongs to the transferrin family. Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and lactoferroxin C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. Lactoferrin / LTF is a globular glycoprotein that is widely represented in various secretory fluids, such as milk, saliva, tears, and nasal secretions. Lactoferrin / LTF is also present in secondary granules of PMN and is secreted by some acinar cells. Lactoferrin / LTF can be purified from milk or produced recombinantly. Human colostrum has the highest concentration, followed by human milk, then cow milk. Lactoferrin / LTF is one of the components of the immune system of the body; it has antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses. In particular, lactoferrin provides antibacterial activity to human infants. Lactoferrin interacts with DNA and RNA, polysaccharides and heparin, and shows some of its biological functions in complexes with these ligands.

Full Name
lactotransferrin
References
  • Sánchez L, et al.,1992, Arch. Dis. Child. 67 (5): 657 - 61.
  • Wakabayashi H, et al., 2000, J. Antimicrob. Chemother. 46 (4): 595-602.
  • Nozaki A, et al., 2003, J. Biol. Chem. 278 (12): 10162-73.
  • Azzam HS, et al., 2007, Liver Int. 27 (1): 17-25.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Lactoferrin Antibody Rabbit Polyclonal ELISA 50750-RP01
    Anti-Lactoferrin Antibody Rabbit Polyclonal ELISA 50750-T16
    Anti-Lactoferrin Antibody Rabbit Monoclonal ELISA 50750-R002
    Anti-Lactoferrin Antibody Mouse Monoclonal ELISA 11096-MM09
    Anti-Lactoferrin Antibody Rabbit Monoclonal ELISA,ELISA(Det) 11096-R006
    Anti-Lactoferrin Antibody Rabbit Polyclonal ELISA 11096-RP01
    Anti-Lactoferrin Antibody Rabbit Monoclonal ELISA(Cap) 11096-R103
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