LRRN3 Protein Price Inquiry ( Available Sizes )
LRRN3 Protein Product Information
||Nbla10363, FIGLER5, FLJ11129, NLRR-3, NLRR3
||A DNA sequence encoding the human LRRN3 (AAH35133.1) extracellular domain (Met 1- Thr 628) was fused with a polyhistidine tag at the C-terminus.
LRRN3 Protein QC Testing
||> 90 % as determined by SDS-PAGE.
||< 1.0 EU per μg of the protein as determined by the LAL method
||Samples are stable for up to twelve months from date of receipt at -70℃
|Predicted N terminal:
||The recombinant human LRRN3 consists of 616 amino acids and predicts a molecular mass of 70 kDa as estimated in SDS-PAGE under reducing conditions.
||Lyophilized from sterile 20mM Tris, 500mM NaCl, pH7.0, 10% gly
- Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
- Please contact us for any concerns or special requirements.
LRRN3 Protein Usage Guide
||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
LRRN3 Protein Related Products & Topics
LRRN3 Protein Description
Leucine-rich repeat neuronal protein 3, also known as neuronal leucine-rich repeat protein 3 (NLRR-3), is a member of leucine-rich(LRR) family whose members have significant functions in neural development. Leucine-rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. All proteins containing these repeats are thought to be involved in protein-protein interactions. The crystal structure of ribonuclease inhibitor protein has revealed that leucine-rich repeats correspond to β-α structural units. These units are arranged so that they form a parallel β-sheet with one surface exposed to solvent, so that the protein acquires an unusual, non-globular shape. These two features may be responsible for the protein-binding functions of proteins containing leucine-rich repeats. LRRN3 plays an important role in cerebellum postnatal development. In a unilateral cortical injury cerebral cortex, NLRR-3 mRNA increased in layers 2-3 which suggests that NLRR-3 may be an important component of the pathophysiological response to brain injury.
- Yang J. et al., 2011, Zhong Nan Da Xue Xue Bao Yi Xue Ban. 36 (5): 424-9.
- Hutcheson HB. et al., 2004, BMC Med Genet. 5 (5): 12.
- Ishii N. et al., 1996, Brain Res Mol Brain Res. 40 (1):148-52.