All LOXL2 reagents are produced in house and quality controlled, including 3 LOXL2 Antibody, 1 LOXL2 ELISA, 12 LOXL2 Gene, 3 LOXL2 Lysate, 3 LOXL2 Protein, 1 LOXL2 qPCR. All LOXL2 reagents are ready to use.
Recombinant LOXL2 proteins are expressed by CHO Stable Cells, HEK293 Cells with fusion tags as C-His.
LOXL2antibodies are validated with different applications, which are IHC-P, ELISA(Cap), ELISA.
LOXL2cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each LOXL2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
LOXL2ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein which belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme activity; and more divergent propeptide regions. LOX family enzyme activities catalyze the final enzymatic conversion required for the formation of normal biosynthetic collagen and elastin cross-links. LOXL2 is expressed by pre-hypertrophic and hypertrophic chondrocytes in vivo, and that LOXL2 expression is regulated in vitro as a function of chondrocyte differentiation. LOXL2 promotes chondrocyte differentiation by mechanisms that are likely to include roles as both a regulator and an effector of chondrocyte differentiation. LOXL2 expression could also be explored as a molecular target in the prevention of breast cancer progression.