Anti-LILRB3 Antibody

Cat: 11978-MM01

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Anti-LILRB3 Antibody (Mouse Monoclonal antibody) General Information
Product name
Anti-LILRB3 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human LILRB3
No cross-reactivity with Human cell lysate (293 cell line) in ELISA.
Recombinant Human LILRB3 Protein (Catalog#11978-H08H)
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LILRB3 (rh LILRB3; Catalog#11978-H08H; NP_006855.2; Met 1-Glu 443). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Monoclonal Mouse IgG1 Clone #5B11H11F1
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-LILRB3 Antibody (Mouse Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  
ELISA(Cap) 1:250-1:2000 This antibody will detect Human LILRB3 in ELISA pair set (Catalog: # SEK11978). In a sandwich ELISA, it can be used as capture antibody.

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-LILRB3 Antibody Alternative Names
Anti-CD85A Antibody;Anti-HL9 Antibody;Anti-ILT-5 Antibody;Anti-ILT5 Antibody;Anti-LILRA6 Antibody;Anti-LIR-3 Antibody;Anti-LIR3 Antibody;Anti-MGC138403 Antibody;Anti-PIRB Antibody;Anti-XXbac-BCX105G6.7 Antibody
LILRB3 Background Information

Leukocyte immunoglobulin-like receptor subfamily B member 3, also known as Leukocyte immunoglobulin-like receptor 3, Immunoglobulin-like transcript 5, Monocyte inhibitory receptor HL9, CD85 antigen-like family member A, CD85a and LILRB3, is a single-pass type I  membrane protein which belongs to the leukocyte receptor cluster (LRC) present on 19q13.4. LILRB3 / CD85a contains four Ig-like C2-type (immunoglobulin-like) domains. LILRB3 / CD85a contains three copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases. LILRB3 / CD85a is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found.

Full Name
leukocyte immunoglobulin like receptor B3
  • Huang,J. et al., 2010, J Virol. 84 (18): 9463-71.
  • Arm J.P. et al., 1997, J. Immunol. 159:2342-2349.
  • Wende H. et al., 2000, Immunogenetics 51:703-713.
  • Yu L.-R. et al., 2007,J. Proteome Res. 6:4150-4162.
  • Product Description Host Clonality Application Catalog# (PDF)
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    Anti-LILRB3 Antibody Mouse Monoclonal FCM 11978-MM08
    Anti-LILRB3 Antibody (FITC) Mouse Monoclonal FCM 11978-MM08-F
    Anti-LILRB3 Antibody Rabbit Polyclonal ELISA 11978-RP01
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