Anti-LILRA5 Antibody

Cat: 80334-RP01
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Anti-LILRA5 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-LILRA5 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Rat
Specificity
Rat LILRA5
Immunogen
Recombinant Rat LILRA5 protein (Catalog#80334-R08H)
Preparation
Produced in rabbits immunized with purified, recombinant Rat LILRA5 (rR LILRA5; Catalog#80334-R08H; D4A6Y0; Met1-Asn248). Total IgG was purified by Protein A affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-LILRA5 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

LILRA5 Background Information

LILRA5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LILR are a family of receptors possessing extracellular immunoglobulin domains. They are also known as CD85, ILTs and LIR, and can exert immunomodulatory effects on a wide range of immune cells. ILT-11 contains 2 Ig-like C2-type (immunoglobulin-like) domains. It can be detected n tissues of the hematopoietic system, including bone marrow, spleen, lymph node and peripheral leukocytes. Crosslink of ILT-11 on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses.

Full Name
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
References
  • Wende H, et al. (2000) Extensive gene duplications and a large inversion characterize the human leukocyte receptor cluster. Immunogenetics. 51(8-9):703-13.
  • Jones DC, et al. (2009) Alternative mRNA splicing creates transcripts encoding soluble proteins from most LILR genes. Eur J Immunol. 39(11):3195-206.
  • Mosbruger TL, et al. (2010) Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. J Infect Dis. 201(9):1371-80.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-LILRA5 Antibody Mouse Monoclonal ELISA(Cap) 80334-MM02
    Anti-LILRA5 Antibody Rabbit Polyclonal ELISA 80334-T16
    Anti-LILRA5 Antibody Rabbit Polyclonal ELISA 16059-RP01
    Anti-LILRA5 Antibody Rabbit Monoclonal ELISA 16059-R018
    Anti-LILRA5 Antibody Rabbit Polyclonal ELISA 16059-T16
    Anti-LILRA5 Antibody Rabbit Polyclonal WB 100481-T32
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