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LDL Receptor / LDLR Antibody (PE), Rabbit MAb

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Human LDLR Antibody Product Information
Immunogen:Recombinant Human LDL Receptor / LDLR protein (Catalog#10231-H08H)
Clone ID:301
Ig Type:Rabbit IgG
Concentration:5 μl/Test, 0.1 mg/ml
Formulation:Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Human LDL Receptor / LDLR (rh LDL Receptor / LDLR; Catalog#10231-H08H; NP_000518.1; Met 1-Arg 788) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Human LDLR Antibody FC Application Image
LDL Receptor / LDLR Antibody (PE), Rabbit MAb, Flow cytometric
[Click to enlarge image]
Caption:
Profile of anti-Human LDLR reactivity on HepG2 cells analyzed by flow cytometry.
Other LDLR Antibody Products
Reactivity: Human  
Application: ELISA  
    10231-RP01-400
    10231-RP01-100
    10231-RP01-200
     
    100 µg 
    200 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      10231-RP02-200
      10231-RP02-50
      10231-RP02-100
      200 µg 
      50 µg 
      100 µg 
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      Reactivity: Human  
      Application: ELISA  
        10231-MM05-200
        10231-MM05-50
        10231-MM05-100
        200 µg 
        50 µg 
        100 µg 
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        Reactivity: Human  
        Application: ELISA  
          10231-R101-50
          10231-R101-100
          50 µg 
          100 µg 
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          Reactivity: Human  
          Application: ELISA  
            10231-R202-50
            10231-R202-100
            50 µg 
            100 µg 
            Add to Cart
            Reactivity: Human  
            Application: FCM  
            • Slide 1
            10231-R301-F-50
            10231-R301-F-100
            50 Tests 
            100 Tests 
            Add to Cart
            Reactivity: Human  
            Application: FCM  
            • Slide 1
            10231-R301-100
            10231-R301-50
            100 µg 
            50 µg 
            Add to Cart
            Reactivity: Human  
            Application: FCM  
            • Slide 1
            10231-R301-A-100
            10231-R301-A-50
            100 Tests 
            50 Tests 
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  
              50305-RP01-100
              50305-RP01-200
              50305-RP01-400
              100 µg 
              200 µg 
               
              Add to Cart
              Reactivity: Mouse  
              Application: ELISA  
                50305-RP02-50
                50305-RP02-100
                50305-RP02-200
                50 µg 
                100 µg 
                200 µg 
                Add to Cart
                Reactivity: Mouse  
                Application: ELISA  IF  ICC/IF  
                • Slide 1
                50305-R032-50
                50305-R032-100
                50 µg 
                100 µg 
                Add to Cart
                Reactivity: Mouse  
                Application: FCM  
                • Slide 1
                50305-R032-C-50
                50305-R032-C-100
                50 Tests 
                100 Tests 
                Add to Cart
                Reactivity: Mouse  
                Application: FCM  
                • Slide 1
                50305-R032-F-50
                50305-R032-F-100
                50 Tests 
                100 Tests 
                Add to Cart
                Reactivity: Mouse  
                Application: FCM  
                • Slide 1
                50305-R032-P-50
                50305-R032-P-100
                50 Tests 
                100 Tests 
                Add to Cart
                Reactivity: Mouse  
                Application: ELISA  IHC-P  
                • Slide 1
                50305-T24-50
                50305-T24-100
                50305-T24-200
                50 µg 
                100 µg 
                200 µg 
                Add to Cart
                LDLR/LDL R/LDL Receptor Background

                LDL Receptor, also known as LDLR, is a mosaic protein which belongs to the Low density lipoprotein receptor gene family. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LDL Receptor consists of 840 amino acids (after removal of signal peptide) and mediates the endocytosis of cholesterol-rich LDL. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. LDL Receptor is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. The receptor also recognizes the apoE protein found in chylomicron remnants and VLDL remnants.

                Human LDLR/LDL R/LDL Receptor References
              • Yamamoto T, et al. (1984) The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA. Cell. 39(1): 27-38.
              • Mao B, et al. (2001) LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature. 411(6835): 321-5.
              • Pinson KI, et al. (2000) An LDL-receptor-related protein mediates Wnt signalling in mice. Nature. 407(6803): 535-8.
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                Catalog: 10231-R301-P-100
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                100 Tests
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                All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"