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LDLR / LDL Receptor Antibody, Rabbit PAb, Antigen Affinity Purified

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Human LDLR Antibody Product Information
Immunogen:Recombinant Human LDLR protein (Catalog#10231-H08H)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:Produced in rabbits immunized with purified, recombinant Human LDLR / LDL Receptor (rh LDLR; Catalog#10231-H08H; NP_000518.1; Met 1-Arg 788). LDLR specific IgG was purified by human LDLR affinity chromatography .
Human LDLR Antibody Usage Guide
Specificity:Human LDLR / LDL Receptor
Application:ELISA

ELISA: 0.5-1.0 μg/mL

This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human LDLR. The detection limit for Human LDLR is 0.00245 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other LDLR Antibody Products
Reactivity: Human  
Application: FCM  
  • Slide 1
10231-R301-P-100
10231-R301-P-50
100 Tests 
50 Tests 
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Reactivity: Human  
Application: ELISA  
    10231-RP01-400
    10231-RP01-100
    10231-RP01-200
     
    100 µg 
    200 µg 
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    Reactivity: Human  
    Application: ELISA  
      10231-MM05-200
      10231-MM05-50
      10231-MM05-100
      200 µg 
      50 µg 
      100 µg 
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      Reactivity: Human  
      Application: ELISA  
        10231-R101-50
        10231-R101-100
        50 µg 
        100 µg 
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        Reactivity: Human  
        Application: ELISA  
          10231-R202-50
          10231-R202-100
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Human  
          Application: FCM  
          • Slide 1
          10231-R301-F-50
          10231-R301-F-100
          50 Tests 
          100 Tests 
          Add to Cart
          Reactivity: Human  
          Application: FCM  
          • Slide 1
          10231-R301-100
          10231-R301-50
          100 µg 
          50 µg 
          Add to Cart
          Reactivity: Human  
          Application: FCM  
          • Slide 1
          10231-R301-A-100
          10231-R301-A-50
          100 Tests 
          50 Tests 
          Add to Cart
          Reactivity: Mouse  
          Application: ELISA  
            50305-RP01-100
            50305-RP01-200
            50305-RP01-400
            100 µg 
            200 µg 
             
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  
              50305-RP02-50
              50305-RP02-100
              50305-RP02-200
              50 µg 
              100 µg 
              200 µg 
              Add to Cart
              Reactivity: Mouse  
              Application: ELISA  IF  ICC/IF  
              • Slide 1
              50305-R032-50
              50305-R032-100
              50 µg 
              100 µg 
              Add to Cart
              Reactivity: Mouse  
              Application: FCM  
              • Slide 1
              50305-R032-C-50
              50305-R032-C-100
              50 Tests 
              100 Tests 
              Add to Cart
              Reactivity: Mouse  
              Application: FCM  
              • Slide 1
              50305-R032-F-50
              50305-R032-F-100
              50 Tests 
              100 Tests 
              Add to Cart
              Reactivity: Mouse  
              Application: FCM  
              • Slide 1
              50305-R032-P-50
              50305-R032-P-100
              50 Tests 
              100 Tests 
              Add to Cart
              LDLR/LDL R/LDL Receptor Background

              LDL Receptor, also known as LDLR, is a mosaic protein which belongs to the Low density lipoprotein receptor gene family. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LDL Receptor consists of 840 amino acids (after removal of signal peptide) and mediates the endocytosis of cholesterol-rich LDL. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. LDL Receptor is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. The receptor also recognizes the apoE protein found in chylomicron remnants and VLDL remnants.

              Human LDLR/LDL R/LDL Receptor References
            • Yamamoto T, et al. (1984) The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA. Cell. 39(1): 27-38.
            • Mao B, et al. (2001) LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature. 411(6835): 321-5.
            • Pinson KI, et al. (2000) An LDL-receptor-related protein mediates Wnt signalling in mice. Nature. 407(6803): 535-8.
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              Catalog: 10231-RP02-200
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              All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
              Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"