Anti-Lipocalin-2 Antibody

Cat: 10222-R210

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Anti-Lipocalin-2 Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-Lipocalin-2 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human Lipocalin-2
No cross-reactivity in ELISA with Human MMP9 Rat LCN2
Recombinant Human LCN2 / NGAL protein (Catalog#10222-H08H)
This antibody was obtained from a rabbit immunized with purified, recombinant Human LCN2 / NGAL (rh LCN2 / NGAL; Catalog#10222-H08H; NP_005555.2; Met 1-Gly 198).
Monoclonal Rabbit IgG Clone #210
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Lipocalin-2 Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Lipocalin-2 Antibody Alternative Names
Anti-24p3 Antibody;Anti-Lipocalin-2 Antibody;Anti-MSFI Antibody;Anti-NGAL Antibody;Anti-p25 Antibody
Lipocalin-2 Background Information

Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells, like kidney tubular cells, may produce NGAL in response to various insults. This protein is released from injured tubular cells after various damaging stimuli, is already known by nephrologists as one of the most promising biomarkers of incoming Acute Kidney Injury (AKI). Recent evidence also suggests its role as a biomarker in a variety of other renal and non-renal conditions. Moreover, recent studies seem to suggest a potential involvement of this factor also in the genesis and progression of chronic kidney diseases. NGAL is the first known mammalian protein which specifically binds organic molecules called siderophores, which are high-affinity iron chelators. NGAL, first known as an antibacterial factor of natural immunity, and an acute phase protein, is currently one of the most interesting and enigmatic proteins involved in the process of tumor development. acting as an intracellular iron carrier and protecting MMP9 from proteolytic degradation, NGAL has a clear pro-tumoral effect, as has already been observed in different tumors (e.g. breast, stomach, oesophagus, brain) in humans. In thyroid carcinomas, NGAL is strongly induced by NF-kB, an important factor involved both in tumor growth and in the link between chronic inflammation and neoplastic development. Thus, Lipocalin-2 (LCN2/NGAL) has been implicated in a variety of processes including cell differentiation, proliferation, survival and morphogenesis.

Full Name
lipocalin 2
  • Schmidt-Ott KM, et al. (2006) Neutrophil gelatinase-associated lipocalin-mediated iron traffic in kidney epithelia. Curr Opin Nephrol Hypertens. 15(4): 442-9.
  • Bolignano D, et al. (2010) Neutrophil gelatinase-associated lipocalin (NGAL) in human neoplasias: a new protein enters the scene. Cancer Lett. 288(1): 10-6.
  • Soni SS, et al. (2010) NGAL: a biomarker of acute kidney injury and other systemic conditions. Int Urol Nephrol. 42(1): 141-50.
  • Bolignano D, et al. (2010) From kidney to cardiovascular diseases: NGAL as a biomarker beyond the confines of nephrology. Eur J Clin Invest. 40(3): 273-6.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Lipocalin-2 Antibody Rabbit Polyclonal ELISA,IHC-P 80058-RP02
    Anti-Lipocalin-2 Antibody Rabbit Monoclonal ELISA 80058-R023
    Anti-Lipocalin-2 Antibody Mouse Monoclonal ELISA 80058-MM04
    Anti-Lipocalin-2 Antibody Rabbit Polyclonal ELISA 80058-RP01
    Anti-Lipocalin-2 Antibody Rabbit Polyclonal ELISA,IHC-P 50060-RP02
    Anti-Lipocalin-2 Antibody Rabbit Monoclonal ELISA 50060-R211
    Anti-Lipocalin-2 Antibody Rabbit Polyclonal ELISA 50060-RP01
    Anti-Lipocalin-2 Antibody Mouse Monoclonal ELISA,IHC-P 10222-MM04
    Anti-Lipocalin-2 Antibody Rabbit Polyclonal WB,ELISA 10222-RP01
    Anti-Lipocalin-2 Antibody Rabbit Polyclonal ELISA,IHC-P 10222-RP02
    Anti-Lipocalin-2 Antibody Rabbit Monoclonal WB,ELISA 10222-R128
    Anti-Lipocalin-2 Antibody Rabbit Polyclonal WB,ELISA 10222-T48
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