|Datasheet||Specific References||Reviews||Related Products||Protocols|
|ORF Clone of Rattus norvegicus lysosomal-associated membrane protein 2 DNA.|
|Identical with the Gene Bank Ref. ID sequence.|
|Whatman FTA elute card (Cat: WB120410) contains 5-10 μg of plasmid.|
|The Whatman FTA elute card can be stored at room temperature for three months under dry condition.|
The pGEM-T is 3kb in length, and contains the amplicin resistance gene, conferring selection of the plasmid in E. coli, and the ori site which is the bacterial origin of replication. The plasmid has multiple cloning sites as shown below. The coding sequence was inserted by TA cloning. Many E. coli strains are suitable for the propagation of this vector including JM109, DH5α and TOP10.
The coding sequence can be easily obtained by digesting the vector with proper restriction enzyme(s). The coding sequence can also be amplified by PCR with M13 primers, or primer pair SP6 and T7.
|Rat LAMP2 Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged||RG80368-G-F|
|Rat LAMP2 Gene cDNA Clone (full-length ORF Clone), expression ready, His-tagged||RG80368-G-H|
|Rat LAMP2 Gene cDNA Clone (full-length ORF Clone), expression ready, Myc-tagged||RG80368-G-M|
|Rat LAMP2 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged||RG80368-G-N|
|Rat LAMP2 Gene cDNA Clone (full-length ORF Clone), expression ready, HA-tagged||RG80368-G-Y|
|Product name||Product name|
LAMP2 (Lysosomal-associated membrane protein 2), also known as CD107b (Cluster of Differentiation 107b), is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. In human, LAMP2, the causative gene of Danon disease, located on chromosome Xq24, encodes the lysosome-associated membrane protein-2 (LAMP-2). LAMP-2 deficiency, or Danon disease, is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. LAMP2 cardiomyopathy is an X-linked and highly progressive myocardial storage disorder associated with diminished survival, which clinically resembles sarcomeric hypertrophic cardiomyopathy.