LAIR2 Matched ELISA Antibody Pair Set,Human

Cat: SEK10868
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LAIR2 Matched ELISA Antibody Pair Set,Human General Information
Product name
LAIR2 Matched ELISA Antibody Pair Set,Human
Assay type
Solid Phase Sandwich ELISA
Specificity
Quantitative determination of Human LAIR2
Assay range
3.91-250
Materials provided
1. Capture Antibody 0.08 mg/mL of rabbit anti-LAIR2 monoclonal antibody. Dilute to a working concentration of 2.0 μg/mL in CBS before coating. (Catalog: # 10868-R001)
2. Detection Antibody 0.5 mg/mL rabbit anti-LAIR2 polyclonal antibody conjugated to horseradish-peroxidase (HRP). Dilute to working concentration of 0.5 μg/mL in detection antibody dilution buffer before use.
3. Standard Each vial contains 17 ng of recombinant LAIR2. Reconstitute standard powder with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 250 pg/mL is recommended.
Product overview
This LAIR2 Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human LAIR2 . It contains Human LAIR2 capture antibody, Human LAIR2 detector antibody (HRP) and a highly purified HEK293-expressed recombinant Human LAIR2 protein. This Pair Set is at affordable price for researchers.
Shipping
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
Storage
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Protect it from prolonged exposure to light. Aliquot and store at -20℃ to -80℃ and for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.
LAIR2 Matched ELISA Antibody Pair Set,Human Images
Human LAIR2 (CD306) ELISA Pair Set Standard Curve 13884
LAIR2 Matched ELISA Antibody Pair Set,Human Alternative Names
CD306 Matched ELISA Antibody Pair Set, Human;LAIR2 Matched ELISA Antibody Pair Set, Human;MGC71634 Matched ELISA Antibody Pair Set, Human;XXbac-BCX535A19.6 Matched ELISA Antibody Pair Set, Human
LAIR2 Background Information

Leukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD306, is a 131 amino acid protein containing one lg-like C2-type domain. It is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. Accordingly, LAIR2 is suggested to perform an immunoregulatory function.

Full Name
leukocyte associated immunoglobulin like receptor 2
References
  • Meyaard, L. et al.,1997, Immunity.7:283-290.
  • Meyaard, L. et al.,1999, J. Immunol. 162:5800-5804.
  • Meyaard, L. et al., 2001,  J. Exp. Med. 194 (1): 107-112.
  • Meyaard, L., 2003, J Biol Regul Homeost Agents.  17 (4): 330-333.
  • Lebbink, R. J. et al., 2008, J Immunol. 180 (3):1662-1669.
  • Lebbink,R.J. et al., 2009,  Matrix Biol.  28 (4):202-210.
  • Product Description Assay Range (pg/ml) Sample Type Catalog# (PDF)
    LAIR2 ELISA Kit, Human Lysate KIT10868
    info info
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