Anti-LAIR2 Antibody (FITC)

Cat: 10868-R024-F
Contact us:
+86-400-890-9989
order@sinobiological.com
Distributors
All LAIR2 Reagents
CRO Services

All LAIR2 Reagents
Anti-LAIR2 Antibody (FITC) (Rabbit Monoclonal antibody) General Information
Product name
Anti-LAIR2 Antibody (FITC)
Validated applications
FCM
Species reactivity
Reacts with: Human
Specificity
Human LAIR2
Immunogen
Recombinant Human LAIR2 protein (Catalog#10868-H08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human LAIR2 (rh LAIR2; Catalog#10868-H08H; NP_002279.2; Met 1-Pro 152) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Source
Monoclonal Rabbit IgG Clone #024
Purification
Protein A
Formulation
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Conjugate
FITC
Concentration
10 μl/Test, 0.1 mg/ml
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Anti-LAIR2 Antibody (FITC) (Rabbit Monoclonal antibody) Validated Applications

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-LAIR2 Antibody (FITC) (Rabbit Monoclonal antibody) Images
Human LAIR2 (CD306) Flow Cytometry (FC) 4841
Flow cytometric analysis of Human LAIR2(CD306) expression in Jurkat cells. The cells were treated according to manufacturer's manual (BD Pharmingen™ Cat. No. 554714), and then stained with FITC Rabbit anti-LAIR2(CD306) (10868-R024-F). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Anti-LAIR2 Antibody (FITC) Alternative Names
Anti-CD306 Antibody;Anti-LAIR2 Antibody;Anti-MGC71634 Antibody;Anti-XXbac-BCX535A19.6 Antibody
LAIR2 Background Information

Leukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD306, is a 131 amino acid protein containing one lg-like C2-type domain. It is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. Accordingly, LAIR2 is suggested to perform an immunoregulatory function.

Full Name
leukocyte associated immunoglobulin like receptor 2
References
  • Meyaard, L. et al.,1997, Immunity.7:283-290.
  • Meyaard, L. et al.,1999, J. Immunol. 162:5800-5804.
  • Meyaard, L. et al., 2001,  J. Exp. Med. 194 (1): 107-112.
  • Meyaard, L., 2003, J Biol Regul Homeost Agents.  17 (4): 330-333.
  • Lebbink, R. J. et al., 2008, J Immunol. 180 (3):1662-1669.
  • Lebbink,R.J. et al., 2009,  Matrix Biol.  28 (4):202-210.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-LAIR2 Antibody Rabbit Polyclonal ELISA 10868-RP01
    Anti-LAIR2 Antibody Rabbit Monoclonal ELISA(Cap) 10868-R001
    Anti-LAIR2 Antibody Rabbit Monoclonal ELISA 10868-R024
    Anti-LAIR2 Antibody Rabbit Polyclonal ELISA 10868-RP02
    info info
    添加购物车成功! 添加购物车失败!