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LAIR2 (CD306) PE Rabbit MAb

  • LAIR2 Antibody (PE), Rabbit MAb, Flow cytometric
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Human LAIR2 Antibody Product Information
Immunogen:Recombinant Human LAIR2 protein (Catalog#10868-H08H)
Clone ID:024
Ig Type:Rabbit IgG
Concentration:5 μl/Test, 0.1 mg/ml
Formulation:Aqueous solution containing 0.5% BSA and 0.1% sodium azide
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Human LAIR2 (rh LAIR2; Catalog#10868-H08H; NP_002279.2; Met 1-Pro 152) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Human LAIR2 Antibody FC Application Image
LAIR2 Antibody (PE), Rabbit MAb, Flow cytometric
[Click to enlarge image]
Caption:
Human LAIR2 (CD306) expression in Jurkat cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and then stained with PE Rabbit anti-LAIR2 (CD306). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Other LAIR2 Antibody Products
Reactivity: Human  
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      10868-R001-50
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        Reactivity: Human  
        Application: ELISA  
          10868-R024-50
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          LAIR2 (CD306) Background

          Leukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD306, is a 131 amino acid protein containing one lg-like C2-type domain. It is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. Accordingly, LAIR2 is suggested to perform an immunoregulatory function.

          Human LAIR2 (CD306) References
        • Meyaard, L. et al.,1997, Immunity.7:283-290.
        • Meyaard, L. et al.,1999, J. Immunol. 162:5800-5804.
        • Meyaard, L. et al., 2001,  J. Exp. Med. 194 (1): 107-112.
        • Meyaard, L., 2003, J Biol Regul Homeost Agents.  17 (4): 330-333.
        • Lebbink, R. J. et al., 2008, J Immunol. 180 (3):1662-1669.
        • Lebbink,R.J. et al., 2009,  Matrix Biol.  28 (4):202-210.
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          All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
          Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"